Synthesis, characterization and biological activity of Co(II), Ni(II), Cu(II) and Cd(II) complexes with new imidazole derivatives [ethyl {[5-oxo-1- (phenylcarbonyl)-4-(prop-1-en-2-yl)-4,5-dihydro-1H-imidazol-2- yl]sulfanyl}acetate]

被引:1
|
作者
Abdullah, Sallal A. H. [1 ]
Faeq, Rana Ismael [2 ]
Kadhem, Noor Abdallah [1 ]
Mohsen, Saif [3 ]
Kadham, Sahar Abdullah [1 ]
机构
[1] Univ Technol Baghdad, Appl Sci Dept, Chem Div, Baghdad, Iraq
[2] Mustansiriyha Univ, Coll Sci, Dept Chem, Baghdad, Iraq
[3] Forens legal Dept, Baghdad, Iraq
来源
EGYPTIAN JOURNAL OF CHEMISTRY | 2023年 / 66卷 / 06期
关键词
1H-imidazol compounds; coordination compound of 1H-imidazol; spectral data; antimicrobial activity; ANTICANCER; DESIGN;
D O I
10.21608/EJCHEM.2022.152031.6586
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The new imidazole ligand have been synthesized from reaction of benzoyl chloride with thiourea, then the resulting product reacted with ethylchloroacetate to produced [ethyl {[4-oxo-1-(phenylcarbonyl)-5-(prop-1-en-2-yl)-4,5-dihydro-1H-imidazol-2- yl]sulfanyl}acetate], This ligand was characterized by C.H.N.S (Elemental analysis), 1H-NMR spectrum, FT-IR spectrum and UV-visible spectra. Metal complexes of this ligand were synthesized and characterized by C.H.N.S (elemental analysis), Magnetic susceptibility, electrical conductance, UV-Vis spectra and FT-IR spectra. The synthesized compounds were screened for its antibacterial and antifungal activity. The result showed that these complexes inhibited the growth of the tested organism.
引用
收藏
页码:129 / 136
页数:8
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