Electrochemical Selenylation of Alkynyl Aryl Ketones: Efficient Synthesis of 3-Selenylated Chromones under Catalyst- and Chemical-Oxidant-Free Conditions

An electrochemical synthesis of various 3-selenylated chromones via selenylation of alkynyl aryl ketones without the employment of catalyst and chemical-oxidant is described here. This method features mild conditions, high efficiency, and wide substrate scope. Furthermore, the scale-up reaction runs smoothly which indicates the practicability of this electrosynthesis strategy. This work describes the electrochemical selenylation of alkynyl aryl ketones, which shows high efficiency in the synthesis of 3-selenylated chromones under transition-metal-free and chemical-oxidant-free conditions. This method features mild conditions, easy operation, and wide substrate scope.+image