Electrochemical Selenylation of Alkynyl Aryl Ketones: Efficient Synthesis of 3-Selenylated Chromones under Catalyst- and Chemical-Oxidant-Free Conditions

被引：6
|
作者：
Cen, Kaili [1 ]
Wei, Jiahao [3 ]
Liu, Yuan [4 ]
Tan, Zhixuan [3 ]
Wang, Xinye [4 ]
Wang, Dahan [2 ]
He, Wei-Min [1 ]
Cai, Jinhui [1 ]
机构：
[1] Univ South China, Coll Chem & Chem Engn, Hengyang 421001, Peoples R China
[2] Shaoyang Univ, Dept Food & Chem Engn, Shaoyang 422100, Peoples R China
[3] Univ South China, Sch Pharmaceut Sci, Hengyang 421001, Peoples R China
[4] Univ South China, Chuanshan Coll, Hengyang 421001, Peoples R China
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年
关键词：
chemical-oxidant-free; electrochemical synthesis; metal-free; 3-selenylated chromones; selenylation; METAL-FREE SYNTHESIS; FLAVONOIDS; ENAMINONES; ANNULATION;
D O I：
10.1002/ejoc.202300968
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An electrochemical synthesis of various 3-selenylated chromones via selenylation of alkynyl aryl ketones without the employment of catalyst and chemical-oxidant is described here. This method features mild conditions, high efficiency, and wide substrate scope. Furthermore, the scale-up reaction runs smoothly which indicates the practicability of this electrosynthesis strategy. This work describes the electrochemical selenylation of alkynyl aryl ketones, which shows high efficiency in the synthesis of 3-selenylated chromones under transition-metal-free and chemical-oxidant-free conditions. This method features mild conditions, easy operation, and wide substrate scope.+image
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页数：6
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