Palladium-Catalyzed Regioselective C-H Oxidative Arylation of 7-Azaindazole N-Oxide at the C6-Position

被引：0
|
作者：
Nassiri, Sarah [1 ,2 ,3 ]
Bousmina, Mostapha [1 ,2 ]
Suzenet, Franck [3 ]
Guillaumet, Gerald [1 ,2 ,3 ]
El Kazzouli, Said [1 ,2 ]
机构：
[1] Euromed Univ Fes UEMF, Euromed Res Ctr, Euromed Fac Pharm, Meknes Rd, Fes 30000, Morocco
[2] Euromed Univ Fes UEMF, Sch Engn Biomed & Biotechnol, Meknes Rd, Fes 30000, Morocco
[3] Univ Orleans, Inst Organ & Analyt Chem, UMR CNRS 7311, BP 6759, F-45067 Orleans 2, France
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年
关键词：
C-H activation; 7-azaindazole N-oxide; oxidative arylation; palladium; regioselectivity; CROSS-COUPLING REACTION; FUNCTIONALIZATION; ARYL; ALKENYLATION; 3-IODOINDAZOLES; DERIVATIVES; OLEFINATION; POSITION; INDOLES; BENZYL;
D O I：
10.1002/ejoc.202300730
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new strategy is reported for the C-H/C-H functionalization of 7-azaindazoles at the C6-position through a regioselective oxidative arylation using N-oxide activation. This methodology allowed selective and original access to C6-arylated 7-azaindazoles with different substituted arenes and heteroarenes.
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页数：7
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