A NIR turn-on fluorescent probe for specific recognition of cysteine and its application in cells and zebrafish

被引:4
|
作者
Zhang, Meng [1 ]
Zhang, Yongbin [2 ]
Huo, Fangjun [2 ]
Chao, Jianbin [3 ]
Shuang, Shaomin [1 ]
机构
[1] Shanxi Univ, Sch Chem & Chem Engn, Taiyuan 030006, Peoples R China
[2] Shanxi Univ, Res Inst Appl Chem, Taiyuan 030006, Peoples R China
[3] Shanxi Univ, Sci Instrument Ctr, Taiyuan 030006, Peoples R China
基金
中国国家自然科学基金;
关键词
Fluorescent probe; Turn-on; Cysteine; Near-infrared; Bioimaging;
D O I
10.1016/j.dyepig.2022.110774
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A new turn-on fluorescent probe (DC-O-SBD) for cysteine (Cys) with a large Stokes shift was synthesized. Free DC-O-SBD had almost no fluorescence. After reacting with Cys, it released near-infrared (NIR) fluorescence at 655 nm. DC-O-SBD can respond to Cys quickly and had high specificity for Cys. Moreover, DC-O-SBD had a low detection limit (0.16 mu M) and a large Stokes shift (155 nm). In addition, DC-O-SBD can efficiently detect Cys in HeLa cells and zebrafish.
引用
收藏
页数:7
相关论文
共 50 条
  • [41] A highly selective turn-on fluorescent and chromogenic probe for CN- and its applications in imaging of living cells and zebrafish in vivo
    Xu, Wan
    Han, Guojiang
    Ma, Pinyi
    Diao, Quanping
    Xu, Longbin
    Liu, Xin
    Sun, Ying
    Wang, Xinghua
    Song, Daqian
    SENSORS AND ACTUATORS B-CHEMICAL, 2017, 251 : 366 - 373
  • [42] "Turn-on" fluorescent probe for selective Cys recognition and the related mechanism
    Duan, Yulian
    Gou, Gao-zhang
    Xu, Jianbin
    Hu, Yubo
    Cheng, Feixiang
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2019, 379 : 1 - 4
  • [43] A fluorescent turn-on probe for detection of hypochlorus acid and its bioimaging in living cells
    Chu, Chien-Ju
    Wu, Guan-Syuan
    Ma, Ho-I
    Venkatesan, Parthiban
    Thirumalaivasan, Natesan
    Wu, Shu-Pao
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2020, 233
  • [44] A near-infrared turn on fluorescent probe for specific detection of cysteine and its application based on a corrole fluorophore
    Lu, Guifen
    Ding, Sihan
    Meng, Suci
    Zhang, Yiming
    DYES AND PIGMENTS, 2024, 227
  • [45] A ratiometric fluorescent probe for cysteine and its application in living cells
    Dai, Xi
    Zhang, Tao
    Liu, Yi-Zhi
    Yan, Tao
    Li, Yun
    Miao, Jun-Ying
    Zhao, Bao-Xiang
    SENSORS AND ACTUATORS B-CHEMICAL, 2015, 207 : 872 - 877
  • [46] A novel colorimetric NIR fluorescent probe for turn-on detection and imaging of hydrogen sulfide
    Lu, Guifen
    Duan, Luyao
    Hu, Qikang
    Meng, Suci
    Cai, Peiyang
    Chen, Yuting
    Wang, Xiaochun
    Dong, Ting
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2024, 448
  • [47] A Significant Fluorescence Turn-On Probe for the Recognition of Al3+ and Its Application
    Xing, Zhiyong
    Wang, Junli
    Huang, Junhui
    Chen, Xiangfeng
    Zong, Ziao
    Fan, Chuanbin
    Huang, Guimei
    MOLECULES, 2022, 27 (08):
  • [48] A hemicyanine-based fluorescent probe for ratiometric detection of ClO-and turn-on detection of viscosity and its imaging application in mitochondria of living cells and zebrafish
    Xu, Si-Lin
    Guo, Fang-Fang
    Xu, Zhi-Hong
    Wang, Yuan
    James, Tony D.
    SENSORS AND ACTUATORS B-CHEMICAL, 2023, 383
  • [49] An NBD-based Fluorescent Turn-on Probe for the Detection of Homocysteine over Cysteine and Its Imaging Applications
    Wang, Jiamin
    Shao, Xiangmin
    Wang, Jianhong
    Shao, Shijun
    CHEMISTRY LETTERS, 2017, 46 (04) : 442 - 445
  • [50] Two-Photon Near Infrared Fluorescent Turn-On Probe Toward Cysteine and Its Imaging Applications
    Wang, Junfeng
    Li, Bin
    Zhao, Weiyu
    Zhang, Xinfu
    Luo, Xiao
    Corkins, Mark E.
    Cole, Sara L.
    Wang, Chao
    Xiao, Yi
    Bi, Xiaoman
    Pang, Yi
    McElroy, Craig A.
    Bird, Amanda J.
    Dong, Yizhou
    ACS SENSORS, 2016, 1 (07): : 882 - 887