Dual wavelengths inverse Spatially Offset Raman Spectroscopy for bone characterization

被引：0
|
作者：
Ma, Hui [1 ,2 ]
Sekar, Sanathana Konugolu Venkata [1 ]
Lanka, Pranav [1 ]
O'Flynn, Carrie [3 ]
Henn, Patrick [3 ]
Andersson-Engels, Stefan [1 ,2 ]
Gautam, Rekha [1 ]
机构：
[1] Tyndall Natl Inst, Lee Maltings Complex, Dyke Parade, Cork T12R5CP, Ireland
[2] Univ Coll Cork, Dept Phys, Coll Rd, Cork T12 K8AF, Ireland
[3] Univ Coll Cork, ASSERT Ctr, Coll Rd, Cork T12 K8AF, Ireland
来源：
ADVANCED BIOMEDICAL AND CLINICAL DIAGNOSTIC AND SURGICAL GUIDANCE SYSTEMS XXI | 2023年 / 12368卷
关键词：
Osteoporosis; Raman; SORS; BMD; Hydration;
D O I：
10.1117/12.2650089
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Osteoporosis is a disease that weakens bones increasing the possibility of bone fracture. The gold standard to diagnose osteoporosis is measuring bone mineral density (BMD). Since BMD only partly determines the strength of the bone, more information on chemical composition and microstructure is needed. Here, we implemented a novel dual-wavelength inverse Spatially Offset Raman Spectroscopy (SORS) to characterize tissue chemical composition covering both the fingerprint and high-wavenumber regions. This system provides a greater probing depth keeping the spectrometer setting constant. The results from hydroxyapatite (HA) and water phantom demonstrate the potential of the Raman system to assess bone mineral and matrix quality in-vivo.
引用
收藏
页数：4
相关论文
共 50 条
  • [1] Dual wavelengths inverse Spatially Offset Raman Spectroscopy for bone characterization
    Ma, Hui
    Sekara, Sanathana Konugolu Venkata
    Lanka, Pranav
    O'Flynn, Carrie
    Henn, Patrick
    Andersson-Engels, Stefan
    Gautam, Rekha
    QUANTUM TECHNOLOGY: DRIVING COMMERCIALISATION OF AN ENABLING SCIENCE III, 2022, 12335
  • [2] Spatially offset Raman spectroscopy for the diagnosis of bone composition
    Cui, Han
    Glidle, Andrew
    Cooper, Jonathan M.
    2020 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO), 2020,
  • [3] Spatially offset Raman spectroscopy
    Mosca, Sara
    Conti, Claudia
    Stone, Nick
    Matousek, Pavel
    NATURE REVIEWS METHODS PRIMERS, 2021, 1 (01):
  • [4] Spatially offset Raman spectroscopy
    Nature Reviews Methods Primers, 1
  • [5] Spatially offset Raman spectroscopy for in vivo bone strength prediction
    Shu, Chi
    Chen, Keren
    Lynch, Maria
    Maher, Jason R.
    Awad, Hani A.
    Berger, Andrew J.
    BIOMEDICAL OPTICS EXPRESS, 2018, 9 (10): : 4781 - 4791
  • [6] Photon migration of Raman signal in bone as measured with spatially offset Raman spectroscopy
    Sowoidnich, Kay
    Churchwell, John H.
    Buckley, Kevin
    Goodship, Allen E.
    Parker, Anthony W.
    Matousek, Pavel
    JOURNAL OF RAMAN SPECTROSCOPY, 2016, 47 (02) : 240 - 247
  • [7] Inverse spatially offset Raman spectroscopy for deep noninvasive probing of turbid media
    Matousek, Pavel
    APPLIED SPECTROSCOPY, 2006, 60 (11) : 1341 - 1347
  • [8] Spatially Offset Raman Spectroscopy for photon migration investigations in long bone
    Sowoidnich, Kay
    Churchwell, John H.
    Buckley, Kevin
    Kerns, Jemma G.
    Goodship, Allen E.
    Parker, Anthony W.
    Matousek, Pavel
    NOVEL BIOPHOTONICS TECHNIQUES AND APPLICATIONS III, 2015, 9540
  • [9] Study on the mineral composition detection in bone by Spatially Offset Raman Spectroscopy
    Liu, Qiushi
    Li, Yuchen
    Zhao, Baozhen
    Gao, Zhixing
    Li, Jing
    Lv, Chong
    Meng, Xianghao
    Zhang, Xiaohua
    AOPC 2019: OPTICAL SPECTROSCOPY AND IMAGING, 2019, 11337
  • [10] Sensitivity of spatially offset Raman spectroscopy (SORS) to subcortical bone tissue
    Feng, Guanping
    Ochoa, Marien
    Maher, Jason R.
    Awad, Hani A.
    Berger, Andrew J.
    JOURNAL OF BIOPHOTONICS, 2017, 10 (08) : 990 - 996
12345