Dual/Multi-Modal Image-Guided Diagnosis and Therapy Based on Luminogens with Aggregation-Induced Emission

被引:0
|
作者
Zhu, Linlin [1 ]
Wu, Wenbo [1 ]
机构
[1] Tianjin Univ, Inst Mol Aggregat Sci, Dept Chem, Tianjin 300072, Peoples R China
来源
MOLECULES | 2024年 / 29卷 / 02期
基金
中国国家自然科学基金;
关键词
aggregation-induced emission; dual/multi-modal imaging; diagnosis; theragnostic; phototherapy; SEMICONDUCTING POLYMER NANOPARTICLES; CHEMICAL PROBES; CONTRAST AGENT; SENSITIVITY; PLATFORM; DYE;
D O I
10.3390/molecules29020371
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The combination of multiple imaging methods has made an indelible contribution to the diagnosis, surgical navigation, treatment, and prognostic evaluation of various diseases. Due to the unique advantages of luminogens with aggregation-induced emission (AIE), their progress has been significant in the field of organic fluorescent contrast agents. Herein, this manuscript summarizes the recent advancements in AIE molecules as contrast agents for optical image-based dual/multi-modal imaging. We particularly focus on the exceptional properties of each material and the corresponding application in the diagnosis and treatment of diseases.
引用
收藏
页数:14
相关论文
共 50 条
  • [31] Dual-targeted activatable photosensitizers with aggregation-induced emission (AIE) characteristics for image-guided photodynamic cancer cell ablation
    Yuan, Youyong
    Xu, Shidang
    Zhang, Chong-Jing
    Zhang, Ruoyu
    Liu, Bin
    JOURNAL OF MATERIALS CHEMISTRY B, 2016, 4 (01) : 169 - 176
  • [32] High-Efficient Clearable Nanoparticles for Multi-Modal Imaging and Image-Guided Cancer Therapy
    Wei, Qiaolin
    Chen, Yao
    Ma, Xibo
    Ji, Jianfeng
    Qiao, Yue
    Zhou, Bo
    Ma, Fei
    Ling, Daishun
    Zhang, Hong
    Tian, Mei
    Tian, Jie
    Zhou, Min
    ADVANCED FUNCTIONAL MATERIALS, 2018, 28 (02)
  • [33] Photoactivatable aggregation-induced emission luminogens based on photodehydrogenation reactions for biomedical applications
    You, Yuanyuan
    Tang, Chengwei
    Lin, Songling
    Zeng, Delong
    Cong, Yanguang
    Wang, Dong
    Chen, Xiaohui
    LUMINESCENCE, 2024, 39 (02)
  • [34] Boosting Luminescence Efficiency of Near-Infrared-II Aggregation-Induced Emission Luminogens via a Mash-Up Strategy of π-Extension and Deuteration for Dual-Model Image-Guided Surgery
    Ma, Fulong
    Jia, Qian
    Deng, Ziwei
    Wang, Bingzhe
    Zhang, Siwei
    Jiang, Jinhui
    Xing, Guichuan
    Wang, Zhongliang
    Qiu, Zijie
    Zhao, Zheng
    Tang, Ben Zhong
    ACS NANO, 2024, 18 (13) : 9431 - 9442
  • [35] Sugar-Based Aggregation-Induced Emission Luminogens: Design, Structures, and Applications
    Wang, Yijia
    Nie, Jingyi
    Fang, Wen
    Yang, Ling
    Hu, Qiaoling
    Wang, Zhengke
    Sun, Jing Zhi
    Tang, Ben Zhong
    CHEMICAL REVIEWS, 2020, 120 (10) : 4534 - 4577
  • [36] Photoactivatable Biomedical Materials Based on Luminogens with Aggregation-Induced Emission (AIE) Characteristics
    Sun, Jiangman
    Li, Hui
    Gu, Xinggui
    Tang, Ben Zhong
    ADVANCED HEALTHCARE MATERIALS, 2021, 10 (24)
  • [37] Fluorescent sensor array based on aggregation-induced emission luminogens for pathogen discrimination
    Li, Zelin
    Xu, Li
    Yuan, Huanxiang
    Zhang, Pengbo
    ANALYST, 2022, 147 (13) : 2930 - 2935
  • [38] Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics
    Zhang, Chong-Jing
    Hu, Qinglian
    Feng, Guangxue
    Zhang, Ruoyu
    Yuan, Youyong
    Lu, Xianmao
    Liu, Bin
    CHEMICAL SCIENCE, 2015, 6 (08) : 4580 - 4586
  • [39] A Versatile Theranostic Nanoplatform with Aggregation-Induced Emission Properties: Fluorescence Monitoring, Cellular Organelle Targeting, and Image-Guided Photodynamic Therapy
    Ma, Haijun
    Li, Ruoxin
    Meng, Haibing
    Tian, Mei
    Zhang, Xianhong
    Liu, Yanling
    Li, Le
    Yuan, Jinying
    Wei, Yen
    SMALL, 2023, 19 (21)
  • [40] Efficient near-infrared photosensitizer with aggregation-induced emission characteristics for mitochondria-targeted and image-guided photodynamic cancer therapy
    Yang, Hanxiao
    Zhuang, Jiabao
    Li, Nan
    Li, Yue
    Zhu, Shiyu
    Hao, Jiaxin
    Xin, Jiayao
    Zhao, Na
    MATERIALS CHEMISTRY FRONTIERS, 2020, 4 (07) : 2064 - 2071