Role of Withania somnifera (Ashwagandha) in the Treatment of Neurological Disorders

被引：2
|
作者：
Sharma, Sonu [1 ]
机构：
[1] Amity Univ, Amity Inst Pharm, Noida, Uttar Pradesh, India
来源：
CURRENT NUTRITION & FOOD SCIENCE | 2023年 / 19卷 / 02期
关键词：
Pharmacological activity; phytoconstituent; Withania somnifera; Ashwagandha; neurological disorder; herbal drug; HERBAL PRODUCTS; PLANT; WITHANOLIDES; HPTLC; ROOT; EXTRACT; GLYCOWITHANOLIDES; QUANTIFICATION; CHROMATOGRAPHY; ANTIOXIDANT;
D O I：
10.2174/1573401318666220415084108
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Different formulations of ashwagandha have been utilized for the treatment of neurological disorders. The present manuscript aimed to discuss various roles of Withania somnifera, (ashwagandha) in the treatment of neurological disorders. In the literature, several neuro-protective phytoconstituents of ashwagandha have been reported, with important pharmacological effects on neurological and brain disorders such as anxiety, Alzheimer's, Parkinson's, and Schizophrenia. Preclinical studies, clinical trials, and patents indicate that Withania somnifera has a wide range of potential as a neuroprotective in several neurological disorders. After a complete literature survey, it can be concluded that Withania somnifera has significant potential to treat neurological disorders.
引用
收藏
页码：158 / 165
页数：8
相关论文
共 50 条
  • [41] Antibacterial and antioxidant activity of different extracts obtained from Withania somnifera (Ashwagandha)
    Kumbukgolla, W. W.
    Attanayake, A. M. H. S.
    Jayaweera, J. A. A. S.
    INTERNATIONAL JOURNAL OF AYURVEDIC MEDICINE, 2021, 12 (04) : 873 - 877
  • [42] Physical properties of Ashwagandha seeds (Withania somnifera L.)-A medicinal crop
    Anandakumar, T. M.
    Kumar, Devendra
    Shivanna, B.
    Kumar, Rakesh
    INDUSTRIAL CROPS AND PRODUCTS, 2022, 186
  • [43] Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation
    Agarwal, R
    Diwanay, S
    Patki, P
    Patwardhan, B
    JOURNAL OF ETHNOPHARMACOLOGY, 1999, 67 (01) : 27 - 35
  • [44] A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction
    Ng, Qin Xiang
    Loke, Wayren
    Foo, Nadine Xinhui
    Tan, Weng Jun
    Chan, Hwei Wuen
    Lim, Donovan Yutong
    Yeo, Wee Song
    PHYTOTHERAPY RESEARCH, 2020, 34 (03) : 583 - 590
  • [45] Major biochemical constituents of Withania somnifera (ashwagandha) extract: A review of chemical analysis
    Abdelwahed, Mahmoud Tareq
    Hegazy, Maha A.
    Mohamed, Ekram H.
    REVIEWS IN ANALYTICAL CHEMISTRY, 2023, 42 (01)
  • [46] Ashwagandha (Withania somnifera) exposures reported to poison centers from 2015 to 2021
    Goertemoeller, Sheila
    Colvin, Jonathan
    Behrman, Alysha
    Yin, Shan
    CLINICAL TOXICOLOGY, 2023, 61 : 110 - 110
  • [47] A biologically active constituent of withania somnifera (Ashwagandha) with anti- stress activity
    Kaur P.
    Mathur S.
    Sharma M.
    Tiwari M.
    Srivastava K.K.
    Chandra R.
    Indian Journal of Clinical Biochemistry, 2001, 16 (2) : 195 - 198
  • [48] P01.44. In vivo immune modulating effects of Ashwagandha (Withania somnifera)
    A Erlandsen
    J Mikolai
    A Murison
    S Mukherjee
    H Zwickey
    BMC Complementary and Alternative Medicine, 12 (Suppl 1):
  • [49] Withania somnifera (Ashwagandha) in neurobehavioural disorders induced by brain oxidative stress in rodents: a systematic review and meta-analysis
    Durg, Sharanbasappa
    Dhadde, Shivsharan B.
    Vandal, Ravichandra
    Shivakumar, Badamaranahalli S.
    Charan, Chabbanahalli S.
    JOURNAL OF PHARMACY AND PHARMACOLOGY, 2015, 67 (07) : 879 - 899
  • [50] An Alternative Treatment for Anxiety: A Systematic Review of Human Trial Results Reported for the Ayurvedic Herb Ashwagandha (Withania somnifera)
    Pratte, Morgan A.
    Nanavati, Kaushal B.
    Young, Virginia
    Morley, Christopher P.
    JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2014, 20 (12) : 901 - 908
12345