Role of Withania somnifera (Ashwagandha) in the Treatment of Neurological Disorders

被引：2
|
作者：
Sharma, Sonu [1 ]
机构：
[1] Amity Univ, Amity Inst Pharm, Noida, Uttar Pradesh, India
来源：
CURRENT NUTRITION & FOOD SCIENCE | 2023年 / 19卷 / 02期
关键词：
Pharmacological activity; phytoconstituent; Withania somnifera; Ashwagandha; neurological disorder; herbal drug; HERBAL PRODUCTS; PLANT; WITHANOLIDES; HPTLC; ROOT; EXTRACT; GLYCOWITHANOLIDES; QUANTIFICATION; CHROMATOGRAPHY; ANTIOXIDANT;
D O I：
10.2174/1573401318666220415084108
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
Different formulations of ashwagandha have been utilized for the treatment of neurological disorders. The present manuscript aimed to discuss various roles of Withania somnifera, (ashwagandha) in the treatment of neurological disorders. In the literature, several neuro-protective phytoconstituents of ashwagandha have been reported, with important pharmacological effects on neurological and brain disorders such as anxiety, Alzheimer's, Parkinson's, and Schizophrenia. Preclinical studies, clinical trials, and patents indicate that Withania somnifera has a wide range of potential as a neuroprotective in several neurological disorders. After a complete literature survey, it can be concluded that Withania somnifera has significant potential to treat neurological disorders.
引用
收藏
页码：158 / 165
页数：8
相关论文
共 50 条
  • [21] Growth and yield performance of ashwagandha (Withania somnifera) under agroforestry
    Thakur, N. S.
    Verma, K. S.
    Rana, R. C.
    INDIAN JOURNAL OF AGRICULTURAL SCIENCES, 2014, 84 (08): : 937 - 941
  • [22] HPTLC Method for Analysis of Withaferin-A in Ashwagandha (Withania somnifera)
    Preeti Sagar Nayak
    Sunil Dutt Upadhyaya
    Anubha Upadhyaya
    JPC – Journal of Planar Chromatography – Modern TLC, 2009, 22 : 197 - 200
  • [23] In Vivo Effects of Ashwagandha (Withania somnifera) Extract on the Activation of Lymphocytes
    Mikolai, Jeremy
    Erlandsen, Andrew
    Murison, Andrew
    Brown, Kimberly A.
    Gregory, William L.
    Raman-Caplan, Padma
    Zwickey, Heather L.
    JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 2009, 15 (04) : 423 - 430
  • [24] Potential clinical applications of Ashwagandha (Withania somnifera) in medicine and neuropsychiatry
    D'Cruz, Migita
    Andrade, Chittaranjan
    EXPERT REVIEW OF CLINICAL PHARMACOLOGY, 2022, 15 (09) : 1067 - 1080
  • [25] Effect on Ashwagandha root powder (Withania somnifera) on performance of broilers
    Samarth, VR
    Jagtap, DG
    Dakshinkar, NP
    Nimbulkar, MV
    Kothekar, MD
    INDIAN VETERINARY JOURNAL, 2002, 79 (07): : 733 - 734
  • [26] HPTLC Method for Analysis of Withaferin-A in Ashwagandha (Withania somnifera)
    Nayak, Preeti Sagar
    Upadhyaya, Sunil Dutt
    Upadhyaya, Anubha
    JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC, 2009, 22 (03) : 197 - 200
  • [27] Ameliorative efficacy of ashwagandha (Withania somnifera) in pesticides intoxicated cockerel
    Varma, Rachna
    Choudhary, G. K.
    Choudhary, P. K.
    Singh, S. P.
    Panwar, H. S.
    INDIAN JOURNAL OF ANIMAL SCIENCES, 2012, 82 (07): : 691 - 696
  • [28] Ameliorative efficacy of ashwagandha (Withania somnifera) in pesticides intoxicated cockerel
    Varma, Rachna
    Choudhary, G. K.
    Choudhary, P. K.
    Singh, S. P.
    Panwar, H. S.
    INDIAN JOURNAL OF ANIMAL SCIENCES, 2011, 81 (11): : 1093 - 1098
  • [29] TISSUE CULTURE, PHYTOCHEMICAL AND ANTIBACTERIAL STUDIES ON Withania somnifera (Ashwagandha)
    Priya, K.
    INTERNATIONAL JOURNAL OF LIFE SCIENCE AND PHARMA RESEARCH, 2020, 10 : 48 - 55
  • [30] Withania somnifera (Ashwagandha) supplementation: a review of its mechanisms, health benefits, and role in sports performance
    Sprengel, Mateusz
    Laskowski, Radoslaw
    Jost, Zbigniew
    NUTRITION & METABOLISM, 2025, 22 (01)
12345