Targeting Venetoclax Resistance in TP53-Mutated Acute Myeloid Leukemia

被引：0
|
作者：
Vanttinen, Ida [1 ,2 ]
Ruokoranta, Tanja [1 ]
Saad, Joseph J. [1 ,2 ]
Kytola, Sari [3 ]
Hellesoy, Monica [4 ]
Gullaksen, Stein-Erik [4 ]
Ettala, Pia-Sofia [5 ]
Pyorala, Marja [6 ]
Rimpilainen, Johanna [7 ]
Siitonen, Timo [8 ]
Wennerberg, Krister [9 ]
Gjertsen, Bjorn T. [4 ,10 ]
Heckman, Caroline A. [1 ,2 ]
Kontro, Mika [1 ,2 ,3 ,11 ]
Kuusanmaki, Heikki [1 ,2 ,9 ,11 ]
机构：
[1] Univ Helsinki, Inst Mol Med Finland FIMM, HiLIFE, Helsinki, Finland
[2] ICAN Digital Precis Canc Med Flagship, Helsinki, Finland
[3] Helsinki Univ Hosp, Dept Hematol, Comprehens Canc Ctr, Helsinki, Finland
[4] Helse Bergen, Hematol Sect, Dept Med, Bergen, Norway
[5] Turku Univ Hosp, Dept Clin Hematol, Turku, Finland
[6] Kuopio Univ Hosp, Dept Med, Kuopio, Finland
[7] Tampere Univ Hosp, Dept Internal Med, Tampere, Finland
[8] Oulu Univ Hosp, Canc Ctr, Hematol, Oulu, Finland
[9] Univ Copenhagen, Biotech Res & Innovat Ctr BRIC, Copenhagen, Denmark
[10] Univ Bergen, Dept Clin Sci, Ctr Canc Biomarkers CCBIO, Bergen, Norway
[11] Fdn Finnish Canc Inst, Helsinki, Finland
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-189340
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
下载
收藏
页数：4
相关论文
共 50 条
  • [21] Immunohistochemistry for p53 Might Lead to Prompter Treatment in TP53-Mutated Acute Myeloid Leukemia
    Boiocchi, Leonardo
    Crabbe, Andrew
    Brunner, Andrew
    Fathi, Amir T.
    Hasserjian, Robert
    Nardi, Valentina
    MODERN PATHOLOGY, 2019, 32
  • [22] Low-dose weekly decitabine and venetoclax in TP53-mutated myeloid malignancies.
    Shapiro, Lauren C.
    Mantzaris, Ioannis
    Shastri, Aditi
    Sica, Alejandro R.
    Bachier-Rodriguez, Lizamarie
    Kornblum, Noah
    Gritsman, Kira
    Feldman, Eric Jay
    Verma, Amit K.
    Braunschweig, Ira
    Saunthararajah, Yogen
    Goldfinger, Mendel
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E19005 - E19005
  • [23] TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Current Guidelines, Therapies, and Future Considerations
    DiGennaro, Jeremy
    Sallman, David A.
    ACTA HAEMATOLOGICA, 2024, 147 (02) : 176 - 186
  • [24] TP53 mutated acute myeloid leukemia
    Sill, H.
    ONCOLOGY RESEARCH AND TREATMENT, 2018, 41 : 257 - 257
  • [25] Optimal Induction and Consolidation Strategy for Patients with Complex Karyotype and TP53-Mutated Acute Myeloid Leukemia
    Jamy, Omer H.
    Diebold, Kendall
    Bachiashvili, Kimo
    Rangaraju, Sravanti
    Vachhani, Pankit
    Godby, Kelly N.
    Salzman, Donna
    Bhatia, Ravi
    BLOOD, 2022, 140 : 8959 - 8960
  • [26] TP53-Mutated Myelodysplastic Syndrome and Acute Myeloid Leukemia: Biology, Current Therapy, and Future Directions
    Daver, Naval G.
    Maiti, Abhishek
    Kadia, Tapan M.
    Vyas, Paresh
    Majeti, Ravindra
    Wei, Andrew H.
    Garcia-Manero, Guillermo
    Craddock, Charles
    Sallman, David A.
    Kantarjian, Hagop M.
    CANCER DISCOVERY, 2022, 12 (11) : 2516 - 2529
  • [27] TP53-mutated acute myeloid leukemia and myelodysplastic syndrome: biology, treatment challenges, and upcoming approaches
    Pereira, Mariana Pinto
    Herrity, Elizabeth
    Kim, Dennis D. H.
    ANNALS OF HEMATOLOGY, 2024, 103 (04) : 1049 - 1067
  • [28] The Current Understanding of and Treatment Paradigm for Newly-Diagnosed TP53-Mutated Acute Myeloid Leukemia
    Shallis, Rory M.
    Stahl, Maximilian
    Bewersdorf, Jan Philipp
    Zeidan, Amer M.
    Testa, Ugo
    Walter, Roland B.
    HEMATO, 2021, 2 (04): : 748 - 763
  • [29] Genomic landscape of TP53-mutated myeloid malignancies
    Abel, Haley J.
    Oetjen, Karolyn A.
    Miller, Christopher A.
    Ramakrishnan, Sai M.
    Day, Ryan B.
    Helton, Nichole M.
    Fronick, Catrina C.
    Fulton, Robert S.
    Heath, Sharon E.
    Tarnawsky, Stefan P.
    Srivatsan, Sridhar Nonavinkere
    Duncavage, Eric J.
    Schroeder, Molly C.
    Payton, Jacqueline E.
    Spencer, David H.
    Walter, Matthew J.
    Westervelt, Peter
    Dipersio, John F.
    Ley, Timothy J.
    Link, Daniel C.
    BLOOD ADVANCES, 2023, 7 (16) : 4586 - 4598
  • [30] TP53-mutated acute myeloid leukemia and myelodysplastic syndrome: biology, treatment challenges, and upcoming approaches
    Mariana Pinto Pereira
    Elizabeth Herrity
    Dennis D.H Kim
    Annals of Hematology, 2024, 103 : 1049 - 1067
12345