Modern hydrologic models have extraordinary capabilities for representing complex process in surface-subsurface systems. These capabilities have revolutionized the way we conceptualize flow systems, but how to represent uncertainty in simulated flow systems is not as well developed. Currently, characterizing model uncertainty can be computationally expensive, in part, because the techniques are appended to the numerical methods rather than seamlessly integrated. The next generation of computers, however, presents opportunities to reformulate the modeling problem so that the uncertainty components are handled more directly within the flow system simulation. Misconceptions about quantum computing abound and they will not be a "silver bullet" for solving all complex problems, but they might be leveraged for certain kinds of highly uncertain problems, such as groundwater (GW). The point of this issue paper is that the GW community could try to revise the foundations of our models so that the governing equations being solved are tailored specifically for quantum computers. The goal moving forward should not just be to accelerate the models we have, but also to address their deficiencies. Embedding uncertainty into the models by evolving distribution functions will make predictive GW modeling more complicated, but doing so places the problem into a complexity class that is highly efficient on quantum computing hardware. Next generation GW models could put uncertainty into the problem at the very beginning of a simulation and leave it there throughout, providing a completely new way of simulating subsurface flows.
机构:
Univ Nottingham, Sch Math Sci, Ctr Math Med & Biol, Univ Pk, Nottingham NG7 2RD, EnglandUniv Nottingham, Sch Math Sci, Ctr Math Med & Biol, Univ Pk, Nottingham NG7 2RD, England
Coombes, Stephen
Byrne, Aine
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Univ Nottingham, Sch Math Sci, Ctr Math Med & Biol, Univ Pk, Nottingham NG7 2RD, EnglandUniv Nottingham, Sch Math Sci, Ctr Math Med & Biol, Univ Pk, Nottingham NG7 2RD, England
Byrne, Aine
NONLINEAR DYNAMICS IN COMPUTATIONAL NEUROSCIENCE,
2019,
: 1
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16
机构:
Univ Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Univ Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, Canc Res UK Edinburgh Ctr, Crewe Rd, Edinburgh EH4 2XU, Midlothian, ScotlandUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Patton, E. Elizabeth
Mueller, Kristen L.
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机构:
Melanoma Res Alliance, 730 15th St NW, Washington, DC 20005 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Mueller, Kristen L.
Adams, David J.
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机构:
Wellcome Sanger Inst, Expt Canc Genet, Cambridge CB10 1SA, EnglandUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Adams, David J.
Anandasabapathy, Niroshana
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机构:
Weill Cornell Med, Dept Dermatol, Meyer Canc Ctr, Program Immunol & Microbial Pathogenesis, New York, NY 10026 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Anandasabapathy, Niroshana
Aplin, Andrew E.
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机构:
Thomas Jefferson Univ, Sidney Kimmel Canc Ctr, Dept Canc Biol, Philadelphia, PA 19107 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Aplin, Andrew E.
Bertolotto, Corine
论文数: 0引用数: 0
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机构:
Univ Cate dAzur, Nice, FranceUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Bertolotto, Corine
Bosenberg, Marcus
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机构:
Yale Univ, Dept Dermatol, New Haven, CT 06520 USA
Yale Univ, Dept Pathol, New Haven, CT USA
Yale Univ, Dept Immunobiol, New Haven, CT USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Bosenberg, Marcus
Ceo, Craig J.
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机构:
Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA USA
Univ Massachusetts, Sch Med, Dept Mol Cell & Canc Biol, Worcester, MA USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Ceo, Craig J.
Burd, Christin E.
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机构:
Ohio State Univ, Dept Mol Genet, Biomed Res Tower,Room 918,460 W 12th Ave, Columbus, OH 43210 USA
Ohio State Univ, Dept Canc Biol, Biomed Res Tower,Room 918,460 W 12th Ave, Columbus, OH 43210 USA
Ohio State Univ, Dept Genet, Biomed Res Tower,Room 918,460 W 12th Ave, Columbus, OH 43210 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Burd, Christin E.
Chi, Ping
论文数: 0引用数: 0
h-index: 0
机构:
Mem Sloan Kettering Canc Ctr, Human Oncol & Pathogenesis Program, 1275 York Ave, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Chi, Ping
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Herlyn, Meenhard
Holmen, Sheri L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Hlth Sci Ctr, Huntsman Canc Inst, Dept Surg, Salt Lake City, UT 84112 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Holmen, Sheri L.
Karreth, Florian A.
论文数: 0引用数: 0
h-index: 0
机构:
H Lee Moffitt Canc Ctr & Res Inst, Dept Mol Oncol, Tampa, FL 33612 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Karreth, Florian A.
Kaufman, Charles K.
论文数: 0引用数: 0
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机构:
Washington Univ, Sch Med, Dept Med, Div Oncol,Dept Dev Biol, McDonnell Sci Bldg,4518 McKinley Ave, St Louis, MO 63110 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Kaufman, Charles K.
Khan, Shaheen
论文数: 0引用数: 0
h-index: 0
机构:
UT Southwestern Med Ctr, Dept Pathol, Dallas, TX USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Khan, Shaheen
Kobold, Sebastian
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机构:
LMU, Klinikum Univ Munchen, Ctr Integrated Prot Sci Munich CIPS M, Munich, Germany
LMU, Klinikum Univ Munchen, Dept Med 4, Div Clin Pharmacol, Munich, GermanyUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Kobold, Sebastian
Leucci, Eleonora
论文数: 0引用数: 0
h-index: 0
机构:
Katholieke Univ Leuven, Lab RNA Canc Biol, Dept Oncol, LKI, B-3000 Leuven, BelgiumUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Leucci, Eleonora
Levy, Carmit
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机构:
Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, IsraelUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Levy, Carmit
Lombard, David B.
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机构:
Univ Michigan, Dept Pathol, Inst Gerontol, Ann Arbor, MI 48109 USA
Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI 48109 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Lombard, David B.
Lund, Amanda W.
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机构:
NYU, Grossman Sch Med, Ronald O Perelman Dept Dermatol, New York, NY 10016 USA
NYU, Grossman Sch Med, Dept Pathol, New York, NY 10016 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Lund, Amanda W.
Marie, Kerrie L.
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机构:
NCI, Lab Canc Biol & Genet, Ctr Canc Res, NIH, Bethesda, MD 20892 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Marie, Kerrie L.
Marine, Jean-Christophe
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机构:
VIB, Lab Mol Canc Biol, Ctr Canc Biol, Leuven, BelgiumUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Marine, Jean-Christophe
Marais, Richard
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机构:
Univ Manchester, CRUK Manchester Inst, Alderley Pk, Macclesfield SK10 4TG, Cheshire, EnglandUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Marais, Richard
McMahon, Martin
论文数: 0引用数: 0
h-index: 0
机构:
Univ Utah, Dept Dermatol, Salt Lake City, UT USA
Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
McMahon, Martin
Robles-Espinoza, Carla Daniela
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机构:
Univ Nacl Autonoma Mexico, Lab Int Invest Genoma Humano, Campus Juriquilla,Blvd Juriquilla 3001, Santiago De Queretaro 76230, MexicoUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Robles-Espinoza, Carla Daniela
Ronai, Ze'ev A.
论文数: 0引用数: 0
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机构:
Sanford Burnham Med Discovery Inst, Canc Ctr, La Jolla, CA 92037 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Ronai, Ze'ev A.
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Samuels, Yardena
Soengas, Maria S.
论文数: 0引用数: 0
h-index: 0
机构:
Spanish Natl Canc Res Ctr, Madrid 28029, SpainUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Soengas, Maria S.
Villanueva, Jessie
论文数: 0引用数: 0
h-index: 0
机构:
Wistar Inst Anat & Biol, Mol & Cellular Oncogenesis Program, 3601 Spruce St, Philadelphia, PA 19104 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
机构:
Mem Sloan Kettering Canc Ctr, Dept Canc Biol & Genet, 1275 York Ave, New York, NY 10021 USA
Mem Sloan Kettering Canc Ctr, Dept Med, 1275 York Ave, New York, NY 10021 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
White, Richard M.
Yeh, Iwei
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Dermatol, San Francisco, CA USA
Univ Calif San Francisco, Dept Pathol, San Francisco, CA 94140 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Yeh, Iwei
Zhu, Jiyue
论文数: 0引用数: 0
h-index: 0
机构:
Washington State Univ, Coll Pharm & Pharmaceut Sci, Dept Pharmaceut Sci, Spokane, WA USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Zhu, Jiyue
Zon, Leonard, I
论文数: 0引用数: 0
h-index: 0
机构:
Harvard Univ, Boston Childrens Hosp, Stem Cell Program, Boston, MA 02115 USA
Harvard Univ, Boston Childrens Hosp, Div Hematol Oncol, Boston, MA 02115 USA
Harvard Univ, Harvard Med Sch, Dana Farber Canc Inst, Howard Hughes Med Inst,Harvard Stem Cell Inst,Ste, Boston, MA 02115 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Zon, Leonard, I
Hurlbert, Marc S.
论文数: 0引用数: 0
h-index: 0
机构:
Melanoma Res Alliance, 730 15th St NW, Washington, DC 20005 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland
Hurlbert, Marc S.
Merlino, Glenn
论文数: 0引用数: 0
h-index: 0
机构:
NCI, Ctr Canc Res, NIH, 37 Convent Dr, Bethesda, MD 20892 USAUniv Edinburgh, Western Gen Hosp, MRC Inst Genet & Mol Med, MRC Human Genet Unit, Crewe Rd, Edinburgh EH4 2XU, Midlothian, Scotland