Large B-cell lymphoma with IRF4 rearrangement-Fine needle biopsy-Report of a case with an atypical presentation

被引:0
|
作者
Barroca, Helena [1 ]
Marques, Cristina [2 ]
Soares, Maria Jose [3 ]
机构
[1] Ctr Hosp Univ S Joao, Serv Anat Patol, Porto, Portugal
[2] Ctr Hosp Univ S Joao, Serv Patol Clin, Porto, Portugal
[3] Ctr Hosp Univ S Joao, Serv Hematol Clin, Porto, Portugal
关键词
cytology; fine needle; FISH; flow cytometry; IRF4; paediatric indolent lymphoma; EXPRESSION;
D O I
10.1002/dc.25211
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
We describe a case of a 17-year-old girl with a mediastinal large B-cell lymphoma with IRF4 rearrangement (LBCL-IRF4r) with an atypical clinical presentation in an unusual location, diagnosed by fine needle biopsy, flow cytometry and FISH. We review the literature and discuss the differential diagnosis, clinical presentation, cytological and immunophenotypical characteristics of this unique case that raises very interesting questions regarding this new entity.
引用
收藏
页码:E322 / E327
页数:6
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