Towards more accurate pharmacogenomic variant effect predictions

被引：1
|
作者：
Park, Yoomi [1 ,2 ]
M Lauschke, Volker [3 ,4 ,5 ]
机构：
[1] Seoul Natl Univ, Coll Med, Seoul Natl Univ Biomed Informat SNUBI, Seoul, South Korea
[2] Seoul Natl Univ, Coll Med, Med Res Ctr, Seoul, South Korea
[3] Dr Margarete F Bosch Inst Clin Pharmacol, Stuttgart, Germany
[4] Karolinska Inst, Dept Physiol & Pharmacol, Stockholm, Sweden
[5] Univ Tubingen, Tubingen, Germany
来源：
PHARMACOGENOMICS | 2023年 / 24卷 / 16期
关键词：
Genomic Medicine; Personalized Drug Response; Precision Medicine; Variant of unknown significance;
D O I：
10.2217/pgs-2023-0187
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Accurate variant interpretation has become a key bottleneck for the translation of an individual's pharmacogenome into actionable recommendations. We recommend an integrated use of multiplexed assays, structure-based predictions and biobank data to develop more accurate effect predictors.
引用
收藏
页码：841 / 844
页数：4
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