Mechanism and design of allosteric activators of SIRT1

被引:4
|
作者
Liu, Fei [1 ,2 ]
Pang, Ningning [1 ,2 ]
Xu, Rui-Ming [3 ]
Yang, Na [1 ,2 ]
机构
[1] Nankai Univ, Key Lab Med Data Anal & Stat Res Tianjin, Tianjin 300353, Peoples R China
[2] Nankai Univ, Coll Pharm, State Key Lab Med Chem Biol, Tianjin 300353, Peoples R China
[3] Chinese Acad Sci, Inst Biophys, CAS Ctr Excellence Biomacromolecules, Natl Lab Biomacromolecules, Beijing 100101, Peoples R China
关键词
SMALL-MOLECULE ACTIVATORS; ADENYLATE KINASE; STRUCTURAL BASIS; STIMULATION; LANDSCAPE; SIRTUINS;
D O I
10.1093/procel/pwac039
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
引用
收藏
页码:387 / 392
页数:6
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