AROuSing SIRT1: Identification of a novel endogenous SIRT1 activator

被引：17
|
作者：
Verdin, Eric [1 ]
机构：
[1] Univ Calif San Francisco, Gladstone Inst Virol & Immunol, San Francisco, CA 94158 USA
来源：
MOLECULAR CELL | 2007年 / 28卷 / 03期
关键词：
D O I：
10.1016/j.molcel.2007.10.013
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
SIRT1 is a protein deacetylase that regulates cellular responses to a variety of stresses. In a recent issue of Molecular Cell, Kim et al. (2007) report the identification of a cellular protein, AROS, that activates the SIRT1-mediated deacetylation of p53.
引用
收藏
页码：354 / 356
页数：3
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