Two new indole alkaloids isolated from a mangrove-derived fungus Colletotrichum sp. HD-1

被引：5

作者：

He, Dan ^{[1
,2
]}

Ma, Qing-Yun ^{[2
]}

Yang, Li ^{[2
]}

Xie, Qing-Yi ^{[2
]}

Zhu, Hong-Juan ^{[1
]}

Dai, Hao-Fu ^{[2
]}

Wu, You-Gen ^{[1
]}

Yang, Dong-Mei ^{[1
,3
,4
]}

Zhao, You -Xing ^{[2
,4
]}

机构：

[1] Hainan Univ, Sanya Nanfan Res Inst, Sanya 572025, Peoples R China

[2] CATAS & Hainan Acad Trop Agr Resource, Inst Trop Biosci & Biotechnol, Haikou Key Lab Res & Utilizat Trop Nat Prod, Haikou 571101, Peoples R China

[3] Hainan Univ, Sch Hort, Key Lab Qual Regulat Trop Hort Crops Hainan Prov, Haikou 570228, Peoples R China

[4] Inst Trop Biosci & Biotechnol, Haikou 571101, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2023年 / 54卷

关键词：

Acrostichum aureum; Endophytic fungi; Colletotrichum sp; Indole alkaloids; Colletotryptin; MARINE; DERIVATIVES; FLAVONOIDS;

D O I：

10.1016/j.phytol.2023.01.015

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new indole alkaloids, colletotryptins G (1) and H (2), along with four known alkaloids (3-6), were isolated from an endophytic fungus Colletotrichum sp. HD-1 (Melanconiaceae) derived from the mangrove plant Acros-tichum aureum (Pteridaceae). The structures of new compounds were elucidated by comprehensive analysis of their UV, HRESIMS, and NMR data. All the isolates were evaluated for their alpha-glucosidase and acetylcholines-terase inhibitory, antibacterial, and antifungal activities. Only compound 2 showed stronger inhibitory activity against alpha-glucosidase with IC50 value of 133.4 mu M than that of the positive control acarbose (319.8 mu M).

引用

页码：81 / 85

页数：5

共 50 条

[11] Secondary Metabolites from the Mangrove-derived Fungus Trichoderma sp.
Zi, Guangrong
Shi, Ying
Hong, Kui
Liu, Ling
NATURAL PRODUCTS JOURNAL, 2024,
[12] A new phenol derivative isolated from mangrove-derived fungus Eupenicillium sp. HJ002
Mei, Rong-Qing
Nong, Xu-Hua
Wang, Bin
Sun, Xue-Ping
Huang, Guo-Lei
Luo, You-Ping
Zheng, Cai-Juan
Chen, Guang-Ying
NATURAL PRODUCT RESEARCH, 2021, 35 (21) : 4051 - 4057
[13] Three new polyketides from a mangrove-derived fungus Colletotrichum gloeosporioides
Luo, You-Ping
Zheng, Cai-Juan
Chen, Guang-Ying
Song, Xiao-Ping
Wang, Zhe
JOURNAL OF ANTIBIOTICS, 2019, 72 (07): : 513 - 517
[14] Three new polyketides from a mangrove-derived fungus Colletotrichum gloeosporioides
You-Ping Luo
Cai-Juan Zheng
Guang-Ying Chen
Xiao-Ping Song
Zhe Wang
The Journal of Antibiotics, 2019, 72 : 513 - 517
[15] A New Polyketide from the Mangrove-Derived Fungus Phomopsis sp. TJM1-5
Xiao-Chen Zhu
Shi-Ji Chen
Guo-Lei Huang
Rong-Qing Mei
Bin Wang
Xue-Ping Sun
Xu-Hua Nong
Jing Xu
Cai-Juan Zheng
Chemistry of Natural Compounds, 2021, 57 : 59 - 62
[16] A New Polyketide from the Mangrove-Derived Fungus Phomopsis sp. TJM1-5
Zhu, Xiao-Chen
Chen, Shi-Ji
Huang, Guo-Lei
Mei, Rong-Qing
Wang, Bin
Sun, Xue-Ping
Nong, Xu-Hua
Xu, Jing
Zheng, Cai-Juan
CHEMISTRY OF NATURAL COMPOUNDS, 2021, 57 (01) : 59 - 62
[17] Metabolites From the Mangrove-Derived Fungus Cladosporium sp. HNWSW-1
Cao, Xi
Guo, Lei
Cai, Caihong
Kong, Fandong
Yuan, Jingzhe
Gai, Cuijuan
Dai, Haofu
Wang, Pei
Mei, Wenli
FRONTIERS IN CHEMISTRY, 2021, 9
[18] Two new bioactive steroids from a mangrove-derived fungus Aspergillus sp
Liu, Zhaoming
Dong, Zhitong
Qiu, Pei
Wang, Qinglin
Yan, Jingjing
Lu, Yongjun
Wasu, Pathom-Aree
Hong, Kui
She, Zhigang
STEROIDS, 2018, 140 : 32 - 38
[19] Two new secondary metabolites from a mangrove-derived fungus Cladosporium sp. JS']JS1-2
Bai, Meng
Zheng, Cai-Juan
Tang, De-Qing
Zhang, Fan
Wang, Hai-Yang
Chen, Guang-Ying
JOURNAL OF ANTIBIOTICS, 2019, 72 (10): : 779 - 782
[20] Two new secondary metabolites from a mangrove-derived fungus Cladosporium sp. JJM22
Wu, Jia-Ting
Zheng, Cai-Juan
Zhang, Bin
Zhou, Xue-Ming
Zhou, Qi
Chen, Guang-Ying
Zeng, Zhuo-Er
Xie, Jin-Long
Han, Chang-Ri
Lyu, Ji-Xing
NATURAL PRODUCT RESEARCH, 2019, 33 (01) : 34 - 40

← 1 2 3 4 5 →