Benzodiazepine;
delirium;
pediatric;
pediatric intensive care unit;
D O I:
10.4103/abr.abr_196_21
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Delirium is a syndrome with an acute onset that is accompanied by fluctuation and is associated with behaviors that indicate impaired consciousness and cognition. It is common and costly and is associated with severe functional decline and distress in an adult. However, its detection and diagnosis are so challenging in children. Herein, we report a 2-year-old girl who was admitted in the pediatric intensive care unit (PICU) with pneumonia and was intubated because of respiratory failure. She needed a lot of benzodiazepine and opioid drugs to be sedated. During hospital course after extubation, she developed by agitation and restlessness and dissociation from environment. Electroencephalography was done and diffuse generalized slow wave was observed. Finally, by environmental factors' correction, benzodiazepine decreasing, and risperidone administering, she became well and discharged. Delirium should be considered as an important, underdiagnosed, and common condition in the PICU. It should be considered in altered cognition, consciousness, and circadian rhythm disturbance situation in children.
机构:
Mem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USAMem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USA
Desai, Sapana
Chau, Terence
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机构:
Mem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USAMem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USA
Chau, Terence
George, Liza
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机构:
Mem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USAMem Hermann Mem City Med Ctr, Dept Pharm, 921 Gessner, Houston, TX 77024 USA
机构:
Mayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Univ Michigan, Sch Med, Dept Pediat, Div Pediat Crit Care Med, Ann Arbor, MI USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Weatherhead, Jeffrey R.
Niedner, Matthew
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机构:
Univ Michigan, Sch Med, Dept Pediat, Div Pediat Crit Care Med, Ann Arbor, MI USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Niedner, Matthew
Dahmer, Mary K.
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h-index: 0
机构:
Univ Michigan, Sch Med, Dept Pediat, Div Pediat Crit Care Med, Ann Arbor, MI USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Dahmer, Mary K.
Malas, Nasuh
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机构:
Univ Michigan, Sch Med, Dept Pediat, Ann Arbor, MI USA
Univ Michigan, Sch Med, Dept Psychiat, Div Child & Adolescent Psychiat, Ann Arbor, MI USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Malas, Nasuh
Owens, Toni
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机构:
Univ Michigan, Sch Med, Dept Pediat, Div Pediat Crit Care Med, Ann Arbor, MI USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA
Owens, Toni
Kawai, Yu
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机构:
Mayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USAMayo Clin, Dept Pediat & Adolescent Med, Div Pediat Crit Care Med, Rochester, MN USA