Benzodiazepine;
delirium;
pediatric;
pediatric intensive care unit;
D O I:
10.4103/abr.abr_196_21
中图分类号:
R-3 [医学研究方法];
R3 [基础医学];
学科分类号:
1001 ;
摘要:
Delirium is a syndrome with an acute onset that is accompanied by fluctuation and is associated with behaviors that indicate impaired consciousness and cognition. It is common and costly and is associated with severe functional decline and distress in an adult. However, its detection and diagnosis are so challenging in children. Herein, we report a 2-year-old girl who was admitted in the pediatric intensive care unit (PICU) with pneumonia and was intubated because of respiratory failure. She needed a lot of benzodiazepine and opioid drugs to be sedated. During hospital course after extubation, she developed by agitation and restlessness and dissociation from environment. Electroencephalography was done and diffuse generalized slow wave was observed. Finally, by environmental factors' correction, benzodiazepine decreasing, and risperidone administering, she became well and discharged. Delirium should be considered as an important, underdiagnosed, and common condition in the PICU. It should be considered in altered cognition, consciousness, and circadian rhythm disturbance situation in children.
机构:
St Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USASt Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USA
Liviskie, Caren
McPherson, Christopher
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机构:
St Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Pediat, Div Newborn Med, St Louis, MO 63110 USASt Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USA
McPherson, Christopher
Luecke, Caitlyn
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机构:
St Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USASt Louis Childrens Hosp, Dept Pharm, St Louis, MO 63110 USA
机构:
Mayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Mayo Clin, Sch Med, Nursing, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Rohlik, Gina M.
Fryer, Karen R.
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h-index: 0
机构:
Mayo Clin, Div Pediat Crit Care Med, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Fryer, Karen R.
Tripathi, Sandeep
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Illinois, Pediat Crit Care Unit, Peoria, IL USA
Univ Illinois, Coll Med, Pediat, Peoria, IL 61656 USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Tripathi, Sandeep
Duncan, Julie M.
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h-index: 0
机构:
Mayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Duncan, Julie M.
Coon, Heather L.
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h-index: 0
机构:
Mayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Coon, Heather L.
Padhya, Dipti R.
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机构:
Mayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
Padhya, Dipti R.
Kahoud, Robert J.
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h-index: 0
机构:
Mayo Clin, Childrens Ctr, Rochester, MN USA
Mayo Clin, Sch Med, Neurol & Pediat, Rochester, MN USAMayo Clin, Childrens Ctr, Pediat Intens Care Unit, Rochester, MN USA
机构:
Univ Florida, Div Pediat, Gainesville, FL USA
Univ Texas Southwestern, Div Pediat Crit Care, Dallas, TX USAUniv Florida, Div Pediat, Gainesville, FL USA
McGetrick, Molly E.
Lach, Caitlin
论文数: 0引用数: 0
h-index: 0
机构:
Univ Florida, Shands Childrens Hosp, 1600 Southwest Archer Rd, Gainesville, FL 32608 USA
Univ Florida, Coll Nursing, Gainesville, FL 32611 USAUniv Florida, Div Pediat, Gainesville, FL USA
Lach, Caitlin
Mullen, Jodi E.
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h-index: 0
机构:
Univ Florida, Shands Childrens Hosp, 1600 Southwest Archer Rd, Gainesville, FL 32608 USAUniv Florida, Div Pediat, Gainesville, FL USA
Mullen, Jodi E.
Munoz-Pareja, Jennifer C.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Florida, Dept Pediat, Div Pediat Crit Care, 1600 Southwest Archer Rd, Gainesville, FL 32608 USAUniv Florida, Div Pediat, Gainesville, FL USA
机构:
Univ Texas MD Anderson Canc Ctr, Div Pharm, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Div Pharm, Houston, TX 77030 USA
Bruno, Jeffrey J.
Warren, Mary Lou
论文数: 0引用数: 0
h-index: 0
机构:
Univ Texas MD Anderson Canc Ctr, Div Nursing, Intens Care Unit, Houston, TX 77030 USAUniv Texas MD Anderson Canc Ctr, Div Pharm, Houston, TX 77030 USA