From the molecular hallmarks to motor behavior: Characterization of a new transgenic mouse model for spinocerebellar ataxia type 2

被引:0
|
作者
Afonso, Ines T. [1 ,2 ,5 ]
Koppenol, Rebekah [1 ,2 ,4 ]
Conceicao, Andre [1 ,2 ,4 ]
Paulino, Rodrigo [1 ]
Mirapalheta, Lourenzo [1 ]
Matos, Carlos A. [1 ,3 ]
Nobrega, Clevio [1 ,3 ]
机构
[1] ABC RI, Faro, Portugal
[2] Fac Med & Ciencias Biomed, PhD Program Biomed Sci, Faro, Portugal
[3] Univ Algarve, Fac Med & Ciencias Biomed, Faro, Portugal
[4] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Coimbra, Portugal
[5] Heidelberg Univ, Interdisciplinary Ctr Neurosci, Heidelberg, Germany
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A 10-02
引用
收藏
页码:69 / 69
页数:1
相关论文
共 50 条
  • [41] Memory decline, anxiety and depression in the mouse model of spinocerebellar ataxia type 3
    Marinina, Ksenia S.
    Bezprozvanny, Ilya B.
    Egorova, Polina A.
    HUMAN MOLECULAR GENETICS, 2024, 33 (04) : 299 - 317
  • [42] Depolarization Block of Purkinje Neurons in a Mouse Model of Spinocerebellar Ataxia Type 3
    Shakkottai, Vikram
    Dell'Orco, James M.
    Paulson, Henry
    NEUROLOGY, 2010, 74 (09) : A486 - A486
  • [43] Transient cerebellar alterations during development prior to obvious motor phenotype in a mouse model of spinocerebellar ataxia type 6
    Jayabal, Sriram
    Ljungberg, Lovisa
    Watt, Alanna J.
    JOURNAL OF PHYSIOLOGY-LONDON, 2017, 595 (03): : 949 - 966
  • [44] A BAC Transgenic Mouse Model of Spinocerebellar Ataxia Type 31 (SCA31) Manifests Late-Onset Motor Dysfunction and RNA Foci in Purkinje Cells
    Sato, Nozomu
    Ishikawa, Kinya
    Niimi, Yusuke
    Mizusawa, Hidehiro
    NEUROLOGY, 2013, 80
  • [45] Progressive degeneration in a new Drosophila model of spinocerebellar ataxia type 7
    Sujkowski, Alyson
    Ranxhi, Bedri
    Bangash, Zoya R.
    Chbihi, Zachary M.
    Prifti, Matthew V.
    Qadri, Zaina
    Alam, Nadir
    Todi, Sokol V.
    Tsou, Wei-Ling
    SCIENTIFIC REPORTS, 2024, 14 (01):
  • [46] Motor Decline in Clinically Presymptomatic Spinocerebellar Ataxia Type 2 Gene Carriers
    Velazquez-Perez, Luis
    Diaz, Rosalinda
    Perez-Gonzalez, Ruth
    Canales, Nalia
    Rodriguez-Labrada, Roberto
    Medrano, Jacquelin
    Sanchez, Gilberto
    Almaguer-Mederos, Luis
    Torres, Cira
    Fernandez-Ruiz, Juan
    PLOS ONE, 2009, 4 (04):
  • [47] Central motor conduction time as prodromal biomarker in spinocerebellar ataxia type 2
    Velazquez-Perez, Luis
    Rodriguez-Labrada, Roberto
    Torres-Vega, Reidenis
    Medrano Montero, Jacqueline
    Vazquez-Mojena, Yaimee
    Auburger, Georg
    Ziemann, Ulf
    MOVEMENT DISORDERS, 2016, 31 (04) : 603 - 604
  • [48] New Model for Estimation of the Age at Onset in Spinocerebellar Ataxia Type 3
    Peng, Linliu
    Chen, Zhao
    Long, Zhe
    Liu, Mingjie
    Lei, Lijing
    Wang, Chunrong
    Peng, Huirong
    Shi, Yuting
    Peng, Yun
    Deng, Qi
    Wang, Shang
    Zou, Guangdong
    Wan, Linlin
    Yuan, Hongyu
    He, Lang
    Xie, Yue
    Tang, Zhichao
    Wan, Na
    Gong, Yiqing
    Hou, Xuan
    Shen, Lu
    Xia, Kun
    Li, Jinchen
    Chen, Chao
    Qiu, Rong
    Klockgether, Thomas
    Tang, Beisha
    Jiang, Hong
    NEUROLOGY, 2021, 96 (23) : E2885 - E2895
  • [49] Rapid Onset of Motor Deficits in a Mouse Model of Spinocerebellar Ataxia Type 6 Precedes Late Cerebellar Degeneration(1,2,3)
    Jayabal, Sriram
    Ljungberg, Lovisa
    Erwes, Thomas
    Cormier, Alexander
    Quilez, Sabrina
    El Jaouhari, Sara
    Watt, Alanna J.
    ENEURO, 2015, 2 (06)
  • [50] IPSC - based model for the study of molecular mechanisms of spinocerebellar ataxia type 1
    Lebedeva, O.
    Surdina, A.
    Bogomiakova, M.
    Kharitonov, A.
    Bogomazova, A.
    Klyushnikov, S.
    Illarioshkin, S.
    Kiselev, S.
    Pozmogova, G.
    Lagarkova, M.
    Volovikov, E.
    FEBS JOURNAL, 2017, 284 : 141 - 141