From the molecular hallmarks to motor behavior: Characterization of a new transgenic mouse model for spinocerebellar ataxia type 2

被引:0
|
作者
Afonso, Ines T. [1 ,2 ,5 ]
Koppenol, Rebekah [1 ,2 ,4 ]
Conceicao, Andre [1 ,2 ,4 ]
Paulino, Rodrigo [1 ]
Mirapalheta, Lourenzo [1 ]
Matos, Carlos A. [1 ,3 ]
Nobrega, Clevio [1 ,3 ]
机构
[1] ABC RI, Faro, Portugal
[2] Fac Med & Ciencias Biomed, PhD Program Biomed Sci, Faro, Portugal
[3] Univ Algarve, Fac Med & Ciencias Biomed, Faro, Portugal
[4] Univ Coimbra, Ctr Neurosci & Cell Biol CNC, Coimbra, Portugal
[5] Heidelberg Univ, Interdisciplinary Ctr Neurosci, Heidelberg, Germany
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A 10-02
引用
收藏
页码:69 / 69
页数:1
相关论文
共 50 条
  • [21] Cerebellar Micro-RNA Profile in a Mouse Model of Spinocerebellar Ataxia Type 2
    Paul, Sharan
    Dansithong, Warunee
    Gandelman, Mandi
    Figueroa, Karla P.
    Scoles, Daniel R.
    Pulst, Stefan M.
    NEUROLOGY-GENETICS, 2024, 10 (02)
  • [22] Glycine Transporter Blockade Ameliorates Motor Ataxia in a Mouse Model of Spinocerebellar Atrophy
    Tanabe, Mitsuo
    Nakano, Tomoharu
    Honda, Motoko
    Ono, Hideki
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2009, 109 (03) : 444 - 448
  • [23] Reversibility of symptoms in a conditional mouse model of spinocerebellar ataxia type 3
    Boy, Jana
    Schmidt, Thorsten
    Wolburg, Hartwig
    Mack, Andreas
    Nuber, Silke
    Boettcher, Martin
    Schmitt, Ina
    Holzmann, Carsten
    Zimmermann, Frank
    Servadio, Antonio
    Riess, Olaf
    HUMAN MOLECULAR GENETICS, 2009, 18 (22) : 4282 - 4295
  • [24] Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model
    Miller, William
    Pruett, Charles Lewis Humphrey
    Stone, William
    Eide, Cindy
    Riddle, Megan
    Popp, Courtney
    Yousefzadeh, Matthew
    Lees, Christopher
    Seelig, Davis
    Thompson, Elizabeth
    Orr, Harry
    Niedernhofer, Laura
    Tolar, Jakub
    PLOS ONE, 2022, 17 (10):
  • [25] Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia
    Hsieh, Jeanne
    Liu, Jen-Wei
    Harn, Horng-Jyh
    Hsueh, Kuo-Wei
    Rajamani, Karthyayani
    Deng, Yu-Chen
    Chia, Chih-Min
    Shyu, Woei-Cheang
    Lin, Shinn-Zong
    Chiou, Tzyy-Wen
    CELL TRANSPLANTATION, 2017, 26 (10) : 1611 - 1621
  • [26] Cerebellar allografts survive and transiently alleviate ataxia in a transgenic model of spinocerebellar ataxia type-1
    Kaemmerer, WF
    Low, WC
    EXPERIMENTAL NEUROLOGY, 1999, 158 (02) : 301 - 311
  • [27] Treadmill training increases the motor activity and neuron survival of the cerebellum in a mouse model of spinocerebellar ataxia type 1
    Chuang, Chieh-Sen
    Chang, Jui-Chih
    Soong, Bing-Wen
    Chuang, Sheng-Fei
    Lin, Ta-Tsung
    Cheng, Wen-Ling
    Orr, Harry T.
    Liu, Chin-San
    KAOHSIUNG JOURNAL OF MEDICAL SCIENCES, 2019, 35 (11): : 679 - 685
  • [28] Non-motor and Extracerebellar Features in Spinocerebellar Ataxia Type 2
    José Luiz Pedroso
    Pedro Braga-Neto
    Marcio Luiz Escorcio-Bezerra
    Agessandro Abrahão
    Marcus Vinicius Cristino de Albuquerque
    Flavio Moura Rezende Filho
    Paulo Victor Sgobbi de Souza
    Wladimir Bocca Vieira de Rezende Pinto
    Franklin Roberto Pereira Borges
    Maria Luiza Saraiva-Pereira
    Laura Bannach Jardim
    Orlando G. P. Barsottini
    The Cerebellum, 2017, 16 : 34 - 39
  • [29] Phenotypic and molecular diversities of spinocerebellar ataxia type 2 in Japan
    Rino Inada
    Makito Hirano
    Nobuyuki Oka
    Makoto Samukawa
    Kazumasa Saigoh
    Hidekazu Suzuki
    Fukashi Udaka
    Akihiro Hashiguchi
    Hiroshi Takashima
    Yukihiro Hamada
    Yusaku Nakamura
    Susumu Kusunoki
    Journal of Neurology, 2021, 268 : 2933 - 2942
  • [30] Phenotypic and molecular diversities of spinocerebellar ataxia type 2 in Japan
    Inada, Rino
    Hirano, Makito
    Oka, Nobuyuki
    Samukawa, Makoto
    Saigoh, Kazumasa
    Suzuki, Hidekazu
    Udaka, Fukashi
    Hashiguchi, Akihiro
    Takashima, Hiroshi
    Hamada, Yukihiro
    Nakamura, Yusaku
    Kusunoki, Susumu
    JOURNAL OF NEUROLOGY, 2021, 268 (08) : 2933 - 2942