Rationale and design of the ABOARD project (A Personalized Medicine Approach for Alzheimer's Disease)

被引:9
|
作者
Dreves, Maria A. E. [1 ,2 ]
van Harten, Argonde [1 ,2 ,3 ]
Visser, Leonie N. C. [1 ,4 ,5 ,6 ]
Rhodius-Meester, Hanneke [1 ,7 ,8 ]
Kohler, Sebastian [9 ]
Kooistra, Minke M. [10 ]
Papma, Janne [11 ,12 ]
Honey, Madison I. J. M. [2 ,3 ]
Blom, Marco M. [10 ]
Smets, Ellen M. A. [4 ,5 ]
de Vugt, Marjolein E.
Teunissen, Charlotte E. [2 ,3 ]
van der Flier, Wiesje [1 ,2 ,9 ,13 ,14 ]
机构
[1] Vrije Univ Amsterdam, Alzheimer Ctr Amsterdam, Neurol, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[2] Vrije Univ Amsterdam, Amsterdam Neurosci, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[3] Vrije Univ Amsterdam, Dept Clin Chem, Neurochem Lab, Amsterdam, Netherlands
[4] Univ Amsterdam, Dept Med Psychol, Amsterdam UMC locat AMC, Amsterdam, Netherlands
[5] Univ Amsterdam, Amsterdam Publ Hlth Res Inst, Qual Care, Amsterdam UMC locat AMC, Amsterdam, Netherlands
[6] Karolinska Inst, Div Clin Geriat, Ctr Alzheimer Res, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden
[7] Vrije Univ Amsterdam, Dept Internal Med, Geriat Med Sect, Amsterdam, Netherlands
[8] Oslo Univ Hosp, Dept Geriat Med, Memory Clin, Oslo, Norway
[9] Maastricht Univ, Sch Mental Hlth & Neurosci, Dept Psychiat & Neuropsychol, Maastricht, Netherlands
[10] Alzheimer Nederland, Amersfoort, Netherlands
[11] Erasmus MC Univ Med Ctr, Dept Neurol, Rotterdam, Netherlands
[12] Erasmus MC Univ Med Ctr, Alzheimer Ctr Erasmus MC, Rotterdam, Netherlands
[13] Vrije Univ Amsterdam, Dept Epidemiol & Data Sci, Amsterdam UMC locat VUmc, Amsterdam, Netherlands
[14] Amsterdam UMC locat VUmc, Alzheimer Ctr Amsterdam, PK 1Z44, Boelelaan 1118, NL-1081 HZ Amsterdam, Netherlands
关键词
Alzheimer's disease; diagnosis; patient-orchestrated care; personalized medicine; prediction; prevention; PREVENTION;
D O I
10.1002/trc2.12401
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The key to stopping Alzheimer's disease (AD) lies in the pre-dementia stages, with the goal to stop AD before dementia has started. We present the rationale and design of the ABOARD (A Personalized Medicine Approach for Alzheimer's Disease) project, which aims to invest in personalized medicine for AD. ABOARD is a Dutch public-private partnership of 32 partners, connecting stakeholders from a scientific, clinical, and societal perspective. The 5-year project is structured into five work packages on (1) diagnosis, (2) prediction, (3) prevention, (4) patient-orchestrated care, and (5) communication and dissemination. ABOARD functions as a network organization in which professionals interact cross-sectorally. ABOARD has a strong junior training program "Juniors On Board." Project results are shared with society through multiple communication resources. By including relevant partners and involving citizens at risk, patients, and their care partners, ABOARD builds toward a future with personalized medicine for AD. HighlightsABOARD (A Personalized Medicine Approach for Alzheimer's Disease) is a public-private research project executed by 32 partners that functions as a network organization.Together, the project partners build toward a future with personalized medicine for Alzheimer's disease.Although ABOARD is a Dutch consortium, it has international relevance.ABOARD improves diagnosis, prediction, prevention, and patient-orchestrated care.
引用
收藏
页数:11
相关论文
共 50 条
  • [11] The Road to Personalized Medicine in Alzheimer's Disease: The Use of Artificial Intelligence
    Silva-Spinola, Anuschka
    Baldeiras, Ines
    Arrais, Joel P.
    Santana, Isabel
    BIOMEDICINES, 2022, 10 (02)
  • [12] Vitamin E and Alzheimer's Disease-Is It Time for Personalized Medicine?
    Cervantes, Breana
    Ulatowski, Lynn M.
    ANTIOXIDANTS, 2017, 6 (03):
  • [13] Nanotechnology in Personalized Medicine: A Promising Tool for Alzheimer's Disease Treatment
    De Matteis, Laura
    Martin-Rapun, Rafael
    de la Fuente, Jesus M.
    CURRENT MEDICINAL CHEMISTRY, 2018, 25 (35) : 4602 - 4615
  • [14] Personalized Medicine for Effective Alzheimer Disease Treatment
    Kosik, Kenneth S.
    JAMA NEUROLOGY, 2015, 72 (05) : 497 - 498
  • [15] Protein structures in Alzheimer's disease: The basis for rationale therapeutic design
    Montoliu-Gaya, Laia
    Villegas, Sandra
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2015, 588 : 1 - 14
  • [16] Treatment of moderate to severe Alzheimer's disease: Rationale and trial design
    Herrmann, Nathan
    CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2007, 34 : S103 - S108
  • [17] Early detection and personalized medicine: Future strategies against Alzheimer's disease
    Di Meco, Antonio
    Vassar, Robert
    MOLECULAR BIOLOGY OF NEURODEGENERATIVE DISEASES: VISIONS FOR THE FUTURE, PT B, 2021, 177 : 157 - 173
  • [18] Amyloid imaging in Alzheimer's disease: a potential new era of personalized medicine?
    Leuzy, Antoine
    Zimmer, Eduardo Rigon
    Gauthier, Serge
    Rosa-Neto, Pedro
    TRANSLATIONAL NEUROSCIENCE, 2014, 5 (01) : 51 - 56
  • [19] Personalized medicine approach in mycobacterial disease
    Mirsaeidi, Mehdi
    INTERNATIONAL JOURNAL OF MYCOBACTERIOLOGY, 2012, 1 (02) : 59 - 64
  • [20] Toward a personalized lifestyle intervention approach to prevent Alzheimer's disease
    Maki, Pauline M.
    MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY, 2019, 26 (01): : 1 - 2