Massive expansion of functional human iPSC-derived cardiomyocytes by concomitant glycogen synthase kinase-3 beta inhibition and removal of cell-cell contact

被引:0
|
作者
Buikema, J. W. [1 ]
Lee, S. [2 ]
Maas, R. G. J. [3 ]
Van der Velden, J. [4 ]
Sluijter, J. P. G. [3 ]
Wu, S. M. [5 ]
机构
[1] Amsterdam Univ Med Ctr, Amsterdam, Netherlands
[2] Sungkyunkwan Univ, Sch Med, Seoul, South Korea
[3] Univ Med Ctr Utrecht, Expt Cardiol, Utrecht, Netherlands
[4] Amsterdam Univ Med Ctr, Physiol, Amsterdam, Netherlands
[5] Stanford Univ, Med Ctr, Cardiovasc Inst, Stanford, CA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [31] GLYCOGEN SYNTHASE KINASE-3β INHIBITION SUPPRESSES EFFECTOR CD4+ T CELL FUNCTION THROUGH METABOLIC REPROGRAMMING
    Mishra, Shravan K.
    Abdelrahman, Leena
    Klatt, Emily
    Faubion, William
    Hirsova, Petra
    Bamidele, Adebowale O.
    GASTROENTEROLOGY, 2024, 166 (05) : S266 - S266
  • [32] Inhibition of glycogen synthase kinase-3β decreases vascular smooth muscle cell growth in vitro through modulation of notch signaling
    Guha, Shaunta T.
    Murphy, Ronan
    Walls, Dermot
    Redmond, Eileen M.
    Cahill, Paul A.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2007, 27 (06) : E135 - E135
  • [33] Glycogen synthase kinase-3 inhibition in glioblastoma multiforme cells induces apoptosis, cell cycle arrest and changing biomolecular structure
    Acikgoz, Eda
    Guler, Gunnur
    Camlar, Mahmut
    Oktem, Gulperi
    Aktug, Huseyin
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2019, 209 : 150 - 164
  • [34] Physiological versus unphysiological cell culture conditions: How the environment alters gene expression, phenotype and functional characterization of human iPSC-derived cardiomyocytes
    Gossmann, Matthias
    Lickiss, Bettina
    Dragicevic, Elena
    Linder, Peter
    Thomas, Ulrich
    George, Michael
    Stoelzle-Feix, Sonja
    Fertig, Niels
    JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, 2022, 117
  • [35] Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    Jason Wray
    Tüzer Kalkan
    Sandra Gomez-Lopez
    Dominik Eckardt
    Andrew Cook
    Rolf Kemler
    Austin Smith
    Nature Cell Biology, 2011, 13 : 838 - 845
  • [36] Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation
    Wray, Jason
    Kalkan, Tuezer
    Gomez-Lopez, Sandra
    Eckardt, Dominik
    Cook, Andrew
    Kemler, Rolf
    Smith, Austin
    NATURE CELL BIOLOGY, 2011, 13 (07) : 838 - U246
  • [37] GLYCOGEN SYNTHASE KINASE-3 (GSK3) ACTIVITY PLAYS CRUCIAL ROLE IN HUMAN PANCREATIC CANCER CELL PROLIFERATION AND SURVIVAL
    Marchand, B.
    Boucher, M. -J.
    PANCREAS, 2008, 37 (04) : 483 - 483
  • [38] miR-203a regulates proliferation, migration, and apoptosis by targeting glycogen synthase kinase-3β in human renal cell carcinoma
    Hu, Guanghui
    Lai, Peng
    Liu, Min
    Xu, Liang
    Guo, Zhuifeng
    Liu, Huan
    Li, Wei
    Wang, Gangchun
    Yao, Xudong
    Zheng, Junhua
    Xu, Yunfei
    TUMOR BIOLOGY, 2014, 35 (11) : 11443 - 11453
  • [39] GLYCOGEN SYNTHASE KINASE-3 INHIBITION ENHANCES C-KIT plus CELL PROLIFERATION AND POST-ISCHEMIC CARDIAC REPAIR
    Qassim, O. E.
    Kamkar, M.
    Molgat, A.
    Jambi, M. M.
    Ye, B.
    Latham, N.
    Davis, D. R.
    CANADIAN JOURNAL OF CARDIOLOGY, 2013, 29 (10) : S345 - S345
  • [40] The B cell antigen receptor regulates the transcriptional activator β-catenin via protein kinase C-mediated inhibition of glycogen synthase kinase-3
    Christian, SL
    Sims, PV
    Gold, MR
    JOURNAL OF IMMUNOLOGY, 2002, 169 (02): : 758 - 769