Metal-free photosensitized aminosulfonylation of alkenes: a practical approach to β-amido sulfones

被引:20
|
作者
Chen, Meiling [1 ]
Sun, Wenyan [1 ]
Yang, Jingjing [1 ]
Yuan, LuLu [1 ]
Chen, Jian-Qiang [1 ]
Wu, Jie [1 ,2 ,3 ]
机构
[1] Taizhou Univ, Inst Adv Studies, Sch Pharmaceut & Chem Engn, 1139 Shifu Ave, Taizhou 318000, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China
基金
中国国家自然科学基金;
关键词
AZA-MICHAEL ADDITION; AMINO SULFONES; STEREOSELECTIVE-SYNTHESIS; SULFUR-DIOXIDE; ENANTIOSELECTIVE SYNTHESIS; INHIBITOR; POTENT; APREMILAST; DISCOVERY; PHOSPHODIESTERASE-4;
D O I
10.1039/d3gc01059g
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A general and environmentally friendly organic photo-induced strategy was developed for the synthesis of diverse alkyl-substituted beta-amino sulfone derivatives, including primary, secondary, and tertiary alkyl-substituted products. Various carboxylic acid derivatives from the simplest acetic acid to sterically bulky tertiary acids can participate in this transformation.
引用
收藏
页码:3857 / 3863
页数:7
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