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Metal-free photosensitized aminosulfonylation of alkenes: a practical approach to β-amido sulfones
被引:20
|作者:
Chen, Meiling
[1
]
Sun, Wenyan
[1
]
Yang, Jingjing
[1
]
Yuan, LuLu
[1
]
Chen, Jian-Qiang
[1
]
Wu, Jie
[1
,2
,3
]
机构:
[1] Taizhou Univ, Inst Adv Studies, Sch Pharmaceut & Chem Engn, 1139 Shifu Ave, Taizhou 318000, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
[3] Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China
基金:
中国国家自然科学基金;
关键词:
AZA-MICHAEL ADDITION;
AMINO SULFONES;
STEREOSELECTIVE-SYNTHESIS;
SULFUR-DIOXIDE;
ENANTIOSELECTIVE SYNTHESIS;
INHIBITOR;
POTENT;
APREMILAST;
DISCOVERY;
PHOSPHODIESTERASE-4;
D O I:
10.1039/d3gc01059g
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
A general and environmentally friendly organic photo-induced strategy was developed for the synthesis of diverse alkyl-substituted beta-amino sulfone derivatives, including primary, secondary, and tertiary alkyl-substituted products. Various carboxylic acid derivatives from the simplest acetic acid to sterically bulky tertiary acids can participate in this transformation.
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页码:3857 / 3863
页数:7
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