Fecal microbiota transplant from common variable immunodeficiency patients to germ-free mice recapitulates gut dysbiosis

被引：0

作者：

Hajjar, Joud ^{[1
]}

Voigt, Anita ^{[2
]}

Conner, Margaret ^{[3
,4
]}

Swennes, Alton ^{[5
,6
]}

Walter, Jolan ^{[7
]}

Butte, Manish ^{[8
,9
]}

Savidge, Tor ^{[10
,11
]}

Oh, Julia ^{[12
]}

Kheradmand, Farrah ^{[13
,14
]}

Petrosino, Joseph ^{[15
]}

机构：

[1] Baylor Coll Med, Houston, TX 77030 USA

[2] Jackson Lab Genom Med, Farmington, CT USA

[3] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA

[4] Baylor Coll Med, Dept Educ Innovat & Technol, Houston, TX 77030 USA

[5] Univ Utah, Sch Med, Off Comparat Med, Salt Lake City, UT USA

[6] Univ Utah, Sch Med, Dept Pathol, Salt Lake City, UT USA

[7] Univ S Florida, Johns Hopkins All Childrens Hosp, Div Pediat Allergy Immunol, St Petersburg, FL USA

[8] Univ Calif Los Angeles, Dept Pediat, Los Angeles, CA 90024 USA

[9] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90024 USA

[10] Baylor Coll Med, Dept Pathol & Immunol, Houston, TX USA

[11] Texas Childrens Hosp, Dept Pathol, Texas Childrens Microbiome Ctr, Houston, TX USA

[12] Jackson Lab Genom Med, Farmington, CT USA

[13] Baylor Coll Med, Biol Inflammat Ctr, Houston, TX USA

[14] Michael E DeBakey Dept Vet Affairs, Ctr Translat Res Inflammatory Dis CTRID, Houston, TX USA

[15] Baylor Coll Med, Dept Mol Virol & Microbiol, Alkek Ctr Metagen & Microbiome Res, Houston, TX USA

来源：

CLINICAL IMMUNOLOGY | 2023年 / 250卷

关键词：

Microbiome; CVID; Non-infectious complications; Germ-free mice; Fecal Microbiome Transfer; Immune Dysregulation;

D O I：

10.1016/j.clim.2023.109362

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页数：3

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