Fecal microbiota transplant from common variable immunodeficiency patients to germ-free mice recapitulates gut dysbiosis

被引：0
|
作者：
Hajjar, Joud [1 ]
Voigt, Anita [2 ]
Conner, Margaret [3 ,4 ]
Swennes, Alton [5 ,6 ]
Walter, Jolan [7 ]
Butte, Manish [8 ,9 ]
Savidge, Tor [10 ,11 ]
Oh, Julia [12 ]
Kheradmand, Farrah [13 ,14 ]
Petrosino, Joseph [15 ]
机构：
[1] Baylor Coll Med, Houston, TX 77030 USA
[2] Jackson Lab Genom Med, Farmington, CT USA
[3] Baylor Coll Med, Dept Mol Virol & Microbiol, Houston, TX 77030 USA
[4] Baylor Coll Med, Dept Educ Innovat & Technol, Houston, TX 77030 USA
[5] Univ Utah, Sch Med, Off Comparat Med, Salt Lake City, UT USA
[6] Univ Utah, Sch Med, Dept Pathol, Salt Lake City, UT USA
[7] Univ S Florida, Johns Hopkins All Childrens Hosp, Div Pediat Allergy Immunol, St Petersburg, FL USA
[8] Univ Calif Los Angeles, Dept Pediat, Los Angeles, CA 90024 USA
[9] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90024 USA
[10] Baylor Coll Med, Dept Pathol & Immunol, Houston, TX USA
[11] Texas Childrens Hosp, Dept Pathol, Texas Childrens Microbiome Ctr, Houston, TX USA
[12] Jackson Lab Genom Med, Farmington, CT USA
[13] Baylor Coll Med, Biol Inflammat Ctr, Houston, TX USA
[14] Michael E DeBakey Dept Vet Affairs, Ctr Translat Res Inflammatory Dis CTRID, Houston, TX USA
[15] Baylor Coll Med, Dept Mol Virol & Microbiol, Alkek Ctr Metagen & Microbiome Res, Houston, TX USA
来源：
CLINICAL IMMUNOLOGY | 2023年 / 250卷
关键词：
Microbiome; CVID; Non-infectious complications; Germ-free mice; Fecal Microbiome Transfer; Immune Dysregulation;
D O I：
10.1016/j.clim.2023.109362
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
15
引用
收藏
页数：3
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