Photonic Si microwell architectures for rapid antifungal susceptibility determination of Candida auris

被引：0
|
作者：
Heuer, Christopher [1 ,2 ,3 ]
Jiang, Xin [1 ]
Ron, Gali [1 ]
Ternyak, Orna [4 ]
Scheper, Thomas [2 ]
Bahnemann, Janina [3 ]
Segal, Ester [1 ]
机构：
[1] Technion Israel Inst Technol, Dept Biotechnol & Food Engn, IL-3200003 Haifa, Israel
[2] Leibniz Univ Hannover, Inst Tech Chem, D-30167 Hannover, Germany
[3] Univ Augsburg, Inst Phys, D-86159 Augsburg, Germany
[4] Technion Israel Inst Technol, Microand Nanofabricat & Printing Unit, IL-3200003 Haifa, Israel
来源：
CHEMICAL COMMUNICATIONS | 2024年 / 60卷 / 10期
基金：
以色列科学基金会;
关键词：
CLSI BROTH MICRODILUTION; VITEK; 2;
D O I：
10.1039/d3cc04446g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present the application of a photonic silicon chip-based optical sensor system for expeditious and phenotypic antifungal susceptibility testing. This label-free diagnostic assay optically monitors the growth of Candida auris at varying antifungal concentrations on a microwell-structured silicon chip in real-time, and antifungal susceptibility is detected within 6 h, four times faster than in the current gold standard method.
引用
收藏
页码：1305 / 1308
页数：4
相关论文
共 50 条
  • [21] Genomic Diversity across Candida auris Clinical Isolates Shapes Rapid Development of Antifungal Resistance In Vitro and In Vivo
    Burrack, Laura S.
    Todd, Robert T.
    Soisangwan, Natthapon
    Wiederhold, Nathan P.
    Selmecki, Anna
    MBIO, 2022, 13 (04):
  • [22] In Vitro Activity of Essential Oils Distilled from Colombian Plants against Candida auris and Other Candida Species with Different Antifungal Susceptibility Profiles
    Zapata-Zapata, Carolina
    Loaiza-Oliva, Manuela
    Martinez-Pabon, Maria C.
    Stashenko, Elena E.
    Mesa-Arango, Ana C.
    MOLECULES, 2022, 27 (20):
  • [23] Candida auris: Epidemiology, Diagnosis, Pathogenesis, Antifungal Susceptibility, and Infection Control Measures to Combat the Spread of Infections in Healthcare Facilities
    Ahmad, Suhail
    Alfouzan, Wadha
    MICROORGANISMS, 2021, 9 (04)
  • [24] Candida auris - Comparison of sensititre YeastOne and Vitek 2 AST systems for antifungal susceptibility testing - A single centre experience
    Patwardhan, Sampada A.
    Prayag, Parikshit S.
    Soman, Rajeev N.
    Purandare, Bharat D.
    Ramya, S.
    Dawra, Romika
    Joshi, Rasika
    Prayag, Amrita P.
    INDIAN JOURNAL OF MEDICAL MICROBIOLOGY, 2024, 50
  • [25] Overestimation of Amphotericin B Resistance in Candida auris with Sensititre YeastOne Antifungal Susceptibility Testing: a Need for Adjustment for Correct Interpretation
    Siopi, Maria
    Peroukidou, Ilektra
    Beredaki, Maria-Ioanna
    Spruijtenburg, Bram
    de Groot, Theun
    Meis, Jacques F.
    Vrioni, Georgia
    Tsakris, Athanasios
    Pournaras, Spyros
    Meletiadis, Joseph
    MICROBIOLOGY SPECTRUM, 2023, 11 (03):
  • [26] Clinical profile, antifungal susceptibility, and molecular characterization of Candida auris isolated from patients in a South Indian surgical ICU
    Umamaheshwari, Shivaswamy
    Neelambike, Sumana Mahadevaiah
    Shankarnarayan, Shamanth Adekhandi
    Kumarswamy, Keerthi Sravanur
    Gopal, Shubha
    Prakash, Hariprasath
    Rudramurthy, Shivaprakash Mandya
    JOURNAL DE MYCOLOGIE MEDICALE, 2021, 31 (04):
  • [27] Candida auris Isolates of the Southern Asian and South African Lineages Exhibit Different Phenotypic and Antifungal Susceptibility Profiles In Vitro
    Szekely, Adrien
    Borman, Andrew M.
    Johnson, Elizabeth M.
    JOURNAL OF CLINICAL MICROBIOLOGY, 2019, 57 (05)
  • [28] In Vitro Antifungal Susceptibility of the Emerging Multidrug-Resistant Pathogen Candida auris to Miltefosine Alone and in Combination with Amphotericin B
    Wu, Yongqin
    Totten, Marissa
    Memon, Warda
    Ying, Chunmei
    Zhang, Sean X.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2020, 64 (02)
  • [29] Antifungal susceptibility pattern of Candida auris strains: Analysis of clinical strains in a tertiary-care educational university hospital
    Khairy, Amira
    Hejres, Suha
    Elbahr, Umran
    Dayyab, Farouq
    Delos Reyes, Clark Steven
    Pastrana, Jennie Ann
    Vineeth, Chithra
    Sudha, Shruti Prem
    Keskin, Ozge
    Rana, Shiv Singh
    Fadel, Elias
    Erdem, Hakan
    Sipahi, Oguz Resat
    NEW MICROBIOLOGICA, 2024, 47 (02): : 152 - 156
  • [30] Determination of amphotericin B antifungal susceptibility in Candida strains using an inverted microscope
    Vural, Demet Gur
    Cetin, Gulsen
    Bilgin, Kemal
    Cayci, Yeliz Tanriverdi
    Birinci, Asuman
    JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, 2024, 18 (02): : 303 - 308
12345