P53 regulates mitochondrial function and biogenesis in therapy induced senescence: a role for 4-aminobutyrate aminotransferase (ABAT)

被引：0
|
作者：
Martinez, Jennyfer [1 ]
Tarallo, Domenica [2 ]
Leyva, Alejandro [3 ,4 ]
Duran, Rosario [5 ]
Moreno, Maria [6 ]
Quijano, Celia [7 ]
机构：
[1] Univ Republica, Bioquim, Montevideo, Uruguay
[2] Univ Republica, Fac Med, Bioquim CEINBIO, Montevideo, Uruguay
[3] Inst Pasteur Montevideo, Montevideo, Uruguay
[4] Inst Invest Biol Clemente Estable IIBCE, Montevideo, Uruguay
[5] IIBCE Inst Pasteur Montevideo Uruguay, Analyt Biochem & Prote Unit, Montevideo, Uruguay
[6] Univ Republica, Inst Higiene, Fac Med, Dept Desarrollo Biotecnol, Montevideo, Uruguay
[7] Univ Republica, Fac Med, Bioquim CEINBIO, Montevideo, Uruguay
来源：
FREE RADICAL BIOLOGY AND MEDICINE | 2023年 / 208卷
关键词：
D O I：
10.1016/j.freeradbiomed.2023.10.160
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
147
引用
收藏
页码：S71 / S72
页数：2
相关论文
共 50 条
  • [41] The role of p53 and cell death by apoptosis and necrosis in 4-hydroperoxycyclophosphamide-induced limb malformations
    Moallem, SA
    Hales, BF
    DEVELOPMENT, 1998, 125 (16): : 3225 - 3234
  • [42] Cancer-associated S100P protein binds and inactivates p53, permits therapy-induced senescence and supports chemoresistance
    Gibadulinova, Adriana
    Pastorek, Michal
    Filipcik, Pavel
    Radvak, Peter
    Csaderova, Lucia
    Vojtesek, Borivoj
    Pastorekova, Silvia
    ONCOTARGET, 2016, 7 (16) : 22508 - 22522
  • [43] The role of p53 protein and TP53 gene during rat oral carcinogenesis induced by 4NQO
    Minicucci, E. M.
    Ribeiro, D. A.
    Silva, G. N.
    Guimaraes, J.
    Salvadori, D. M. F.
    ORAL ONCOLOGY, 2009, : 218 - 219
  • [44] Role of p16(INK4A) in Replicative Senescence and DNA Damage-Induced Premature Senescence in p53-Deficient Human Cells
    Mirzayans, Razmik
    Andrais, Bonnie
    Hansen, Gavin
    Murray, David
    BIOCHEMISTRY RESEARCH INTERNATIONAL, 2012, 2012
  • [45] Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells
    Subburayan, Karthikeyan
    Thayyullathil, Faisal
    Pallichankandy, Siraj
    Rahman, Anees
    Galadari, Sehamuddin
    CANCER LETTERS, 2018, 426 : 80 - 97
  • [46] Caveolin-1 regulates oxidative stress-induced senescence in nucleus pulposus cells primarily via the p53/p21 signaling pathway in vitro
    Ding, Lei
    Zeng, Qingmin
    Wu, Jingping
    Li, Defang
    Wang, Houlei
    Lu, Wei
    Jiang, Zengxin
    Xu, Guoxiong
    MOLECULAR MEDICINE REPORTS, 2017, 16 (06) : 9521 - 9527
  • [47] Epigenetic silencing of ALX4 regulates microcystin-LR induced hepatocellular carcinoma through the P53 pathway
    Zhao, Ji
    Chen, Hong-qiang
    Yang, Hui-fang
    Li, Yan
    Chen, Dong-jiao
    Huang, Yu-jing
    He, Li-xiong
    Zheng, Chuan-fen
    Wang, Ling-qiao
    Wang, Jia
    Zhang, Na
    Cao, Jia
    Liu, Jin-yi
    Shu, Wei-qun
    Liu, Wen-bin
    SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 683 : 317 - 330
  • [48] The Role of JNK and p53 in the Regulation of Secretory Function of Neuroglial Cells of Various Types in β-Amyloid-Induced Neurodegeneration
    Zyuz'kov, G. N.
    Miroshnichenko, L. A.
    Chaikovskii, A. V.
    Kotlovskaya, L. Yu.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2023, 175 (06) : 753 - 756
  • [49] The Role of JNK and p53 in the Regulation of Secretory Function of Neuroglial Cells of Various Types in β-Amyloid-Induced Neurodegeneration
    G. N. Zyuz’kov
    L. A. Miroshnichenko
    A. V. Chaikovskii
    L. Yu. Kotlovskaya
    Bulletin of Experimental Biology and Medicine, 2023, 175 : 753 - 756
  • [50] Contribution of p16INK4a and p21CIP1 pathways to induction of premature senescence of human endothelial cells:: permissive role of p53
    Chen, J
    Huang, X
    Halicka, D
    Brodsky, S
    Avram, A
    Eskander, J
    Bloomgarden, NA
    Darzynkiewicz, Z
    Goligorsky, MS
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 290 (04): : H1575 - H1586
12345