P53 regulates mitochondrial function and biogenesis in therapy induced senescence: a role for 4-aminobutyrate aminotransferase (ABAT)

被引:0
|
作者
Martinez, Jennyfer [1 ]
Tarallo, Domenica [2 ]
Leyva, Alejandro [3 ,4 ]
Duran, Rosario [5 ]
Moreno, Maria [6 ]
Quijano, Celia [7 ]
机构
[1] Univ Republica, Bioquim, Montevideo, Uruguay
[2] Univ Republica, Fac Med, Bioquim CEINBIO, Montevideo, Uruguay
[3] Inst Pasteur Montevideo, Montevideo, Uruguay
[4] Inst Invest Biol Clemente Estable IIBCE, Montevideo, Uruguay
[5] IIBCE Inst Pasteur Montevideo Uruguay, Analyt Biochem & Prote Unit, Montevideo, Uruguay
[6] Univ Republica, Inst Higiene, Fac Med, Dept Desarrollo Biotecnol, Montevideo, Uruguay
[7] Univ Republica, Fac Med, Bioquim CEINBIO, Montevideo, Uruguay
关键词
D O I
10.1016/j.freeradbiomed.2023.10.160
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
147
引用
收藏
页码:S71 / S72
页数:2
相关论文
共 50 条
  • [31] Bach1 inhibits oxidative stress–induced cellular senescence by impeding p53 function on chromatin
    Yoshihiro Dohi
    Tsuyoshi Ikura
    Yutaka Hoshikawa
    Yasutake Katoh
    Kazushige Ota
    Ayako Nakanome
    Akihiko Muto
    Shinji Omura
    Tsutomu Ohta
    Akihiro Ito
    Minoru Yoshida
    Tetsuo Noda
    Kazuhiko Igarashi
    Nature Structural & Molecular Biology, 2008, 15 : 1246 - 1254
  • [32] Reduced carbohydrate availability enhances exercise-induced p53 signaling in human skeletal muscle: implications for mitochondrial biogenesis
    Bartlett, Jonathan D.
    Louhelainen, Jari
    Iqbal, Zafar
    Cochran, Andrew J.
    Gibala, Martin J.
    Gregson, Warren
    Close, Graeme L.
    Drust, Barry
    Morton, James P.
    AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2013, 304 (06) : R450 - R458
  • [33] Role of p53 and transcription-independent p53-induced apoptosis in shear-stimulated megakaryocytic maturation, particle generation, and platelet biogenesis
    Luff, Stephanie A.
    Kao, Chen-Yuan
    Papoutsakis, Eleftherios T.
    PLOS ONE, 2018, 13 (09):
  • [34] p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse
    Memme, Jonathan M.
    Oliveira, Ashley N.
    Hood, David A.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2022, 298 (02)
  • [35] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin
    Dohi, Yoshihiro
    Ikura, Tsuyoshi
    Hoshikawa, Yutaka
    Katoh, Yasutake
    Ota, Kazushige
    Nakanome, Ayako
    Muto, Akihiko
    Omura, Shinji
    Ohta, Tsutomu
    Ito, Akihiro
    Yoshida, Minoru
    Noda, Tetsuo
    Igarashi, Kazuhiko
    NATURE STRUCTURAL & MOLECULAR BIOLOGY, 2008, 15 (12) : 1246 - 1254
  • [36] Inhibition of p53 preserves mitochondrial morphology and function, and prevents glutamate-induced cell death in neurons
    Diemert, S.
    Grohm, J.
    Hartmannsgruber, R.
    Culmsee, C.
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2009, 379 : 23 - 23
  • [37] Apoptotic mitochondrial dysfunction induced by benzo(a)pyrene in liver epithelial cells -: Role of p53 and pHi changes
    Huc, L
    Gilot, D
    Gardyn, C
    Rissel, M
    Dimanche-Boitrel, MT
    Guillouzo, AT
    Fardel, O
    Lagadic-Gossmann, D
    APOPTOSIS: FROM SIGNALING PATHWAYS TO THERAPEUTIC TOOLS, 2003, 1010 : 167 - 170
  • [38] Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program
    Mazzucco, Anna E.
    Smogorzewska, Agata
    Kang, Chanhee
    Luo, Ji
    Schlabach, Michael R.
    Xu, Qikai
    Patel, Rupesh
    Elledge, Stephen J.
    GENES & DEVELOPMENT, 2017, 31 (19) : 1933 - 1938
  • [39] Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function
    De Vitto, Humberto
    Ryu, Joohyun
    Calderon-Aparicio, Ali
    Monts, Josh
    Dey, Raja
    Chakraborty, Abhijit
    Lee, Mee-Hyun
    Bode, Ann M.
    Dong, Zigang
    CANCER & METABOLISM, 2020, 8 (01)
  • [40] Estrogen-related receptor alpha directly binds to p53 and cooperatively controls colon cancer growth through the regulation of mitochondrial biogenesis and function
    Humberto De Vitto
    Joohyun Ryu
    Ali Calderon-Aparicio
    Josh Monts
    Raja Dey
    Abhijit Chakraborty
    Mee-Hyun Lee
    Ann M. Bode
    Zigang Dong
    Cancer & Metabolism, 8