Susceptibility of Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis Isolated from Pigs in Hungary between 2018 and 2021

被引:3
|
作者
Somogyi, Zoltan [1 ,2 ]
Mag, Patrik [1 ,2 ]
Simon, Reka [1 ]
Kerek, Adam [1 ,2 ]
Makrai, Laszlo [2 ,3 ]
Biksi, Imre [4 ,5 ]
Jerzsele, Akos [1 ,2 ]
机构
[1] Univ Vet Med, Dept Pharmacol & Toxicol, Istvan Str 2, H-1078 Budapest, Hungary
[2] Univ Vet Med, Natl Lab Infect Anim Dis Antimicrobial Resistance, H-1078 Budapest, Hungary
[3] Univ Vet Med, Dept Microbiol & Infect Dis, Istvan Str 2, H-1078 Budapest, Hungary
[4] Univ Vet Med, Dept Pathol, Istvan Str 2, H-1078 Budapest, Hungary
[5] SCG Diagnost Ltd, HU-2437 Delegyhaza, Hungary
来源
ANTIBIOTICS-BASEL | 2023年 / 12卷 / 08期
关键词
Actinobacillus pleuropneumoniae; Pasteurella multocida; Streptococcus suis; MIC; antibacterial agents; swine; ANTIMICROBIAL SUSCEPTIBILITY; ESCHERICHIA-COLI; EDIBLE TISSUES; UNITED-STATES; RESISTANCE; DISEASE; CANADA;
D O I
10.3390/antibiotics12081298
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Porcine respiratory disease complex (PRDC) has been a major animal health, welfare, and economic problem in Hungary; therefore, great emphasis should be put on both the prevention and control of this complex disease. As antibacterial agents are effective tools for control, antibiotic susceptibility testing is indispensable for the proper implementation of antibacterial therapy and to prevent the spread of resistance. The best method for this is to determine the minimum inhibitory concentration (MIC) by the broth microdilution method. In our study, we measured the MIC values of 164 Actinobacillus pleuropneumoniae, 65 Pasteurella multocida, and 118 Streptococcus suis isolates isolated from clinical cases against the following antibacterial agents: amoxicillin, ceftiofur, cefquinome, oxytetracycline, doxycycline, tylosin, tilmicosin, tylvalosin, tulathromycin, lincomycin, tiamulin, florfenicol, colistin, enrofloxacin, and sulfamethoxazole-trimethoprim. Outstanding efficacy against A. pleuropneumoniae isolates was observed with ceftiofur (100%) and tulathromycin (100%), while high levels of resistance were observed against cefquinome (92.7%) and sulfamethoxazole-trimethoprim (90.8%). Ceftiofur (98.4%), enrofloxacin (100%), florfenicol (100%), and tulathromycin (100%) were found to be highly effective against P. multocida isolates, while 100% resistance was detected against the sulfamethoxazole-trimethoprim combination. For the S. suis isolates, only ceftiofur (100%) was not found to be resistant, while the highest rate of resistance was observed against the sulfamethoxazole-trimethoprim combination (94.3%). An increasing number of studies report multi-resistant strains of all three pathogens, making their monitoring a high priority for animal and public health.
引用
下载
收藏
页数:15
相关论文
共 50 条
  • [31] Evaluation of serovar-independent ELISA antigens of Actinobacillus pleuropneumoniae in pigs, following experimental challenge with A. pleuropneumoniae, Mycoplasma hyopneumoniae and Pasteurella multocida
    Eamens, G. J.
    Gonsalves, J. R.
    Whittington, A-M
    Turner, B.
    AUSTRALIAN VETERINARY JOURNAL, 2012, 90 (06) : 225 - 234
  • [32] STREPTOCOCCUS SUIS ISOLATED FROM PIGS IN FINLAND
    SIHVONEN, L
    KURL, DN
    HENRICHSEN, J
    ACTA VETERINARIA SCANDINAVICA, 1988, 29 (01) : 9 - 13
  • [33] EVALUATION OF THE RAPID NH SYSTEM FOR IDENTIFICATION OF HAEMOPHILUS-SOMNUS, PASTEURELLA-MULTOCIDA, PASTEURELLA-HAEMOLYTICA, AND ACTINOBACILLUS-PLEUROPNEUMONIAE ISOLATED FROM CATTLE AND PIGS WITH RESPIRATORY-DISEASE
    SALMON, SA
    WATTS, JL
    YANCEY, RJ
    JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (05) : 1362 - 1363
  • [34] Optimizing tylosin dosage for co-infection of Actinobacillus pleuropneumoniae and Pasteurella multocida in pigs using pharmacokinetic/pharmacodynamic modeling
    Lee, Eon-Bee
    Abbas, Muhammad Aleem
    Park, Jonghyun
    Tassew, Dereje D.
    Park, Seung-Chun
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [35] Mutant prevention and minimum inhibitory concentration drug values for enrofloxacin, ceftiofur, florfenicol, tilmicosin and tulathromycin tested against swine pathogens Actinobacillus pleuropneumoniae, Pasteurella multocida and Streptococcus suis
    Blondeau, Joseph M.
    Fitch, Shantelle D.
    PLOS ONE, 2019, 14 (01):
  • [36] The Isolation and Identification of Actinobacillus pleuropneumoniae and Antimicrobial Susceptibility From Pigs in China
    Dong, Yongjun
    Wang, Lirong
    Liu, Xingyou
    Zhao, Kun
    JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 2015, 9 (02): : 899 - 911
  • [37] CHARACTERIZATION OF PASTEURELLA MULTOCIDA ISOLATED FROM PNEUMONIC PIGS OF ASSAM
    Hazarika, M. P.
    Barman, N. N.
    George, S.
    Sharma, R. K.
    INDIAN JOURNAL OF ANIMAL RESEARCH, 2010, 44 (04) : 265 - 269
  • [38] Antimicrobial susceptibility of Streptococcus suis isolated from diseased pigs, asymptomatic pigs, and human patients in Thailand
    Suganya Yongkiettrakul
    Krissana Maneerat
    Buppa Arechanajan
    Yuwares Malila
    Potjanee Srimanote
    Marcello Gottschalk
    Wonnop Visessanguan
    BMC Veterinary Research, 15
  • [39] BIOCHEMICAL TRAITS AND ANTIMICROBIAL SUSCEPTIBILITY OF STREPTOCOCCUS-SUIS ISOLATED FROM SLAUGHTERED PIGS
    PRIETO, C
    GARCIA, FJ
    SUAREZ, P
    IMAZ, M
    CASTRO, JM
    JOURNAL OF VETERINARY MEDICINE SERIES B-INFECTIOUS DISEASES AND VETERINARY PUBLIC HEALTH, 1994, 41 (09): : 608 - 617
  • [40] Antimicrobial susceptibility of Streptococcus suis isolated from diseased pigs, asymptomatic pigs, and human patients in Thailand
    Yongkiettrakul, Suganya
    Maneerat, Krissana
    Arechanajan, Buppa
    Malila, Yuwares
    Srimanote, Potjanee
    Gottschalk, Marcello
    Visessanguan, Wonnop
    BMC VETERINARY RESEARCH, 2019, 15 (1)