A biology-aware mutation rate model for human germline

被引：0
|
作者：
Koch, Evan M. [1 ]
Seplyarskiy, Vladimir [1 ]
Sunyaev, Shamil R. [1 ]
机构：
[1] Harvard Med Sch, Dept Biomed Informat, Boston, MA 02115 USA
来源：
NATURE GENETICS | 2023年 / 55卷 / 12期
关键词：
D O I：
10.1038/s41588-023-01564-y
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：2033 / 2034
页数：2
相关论文
共 50 条
  • [41] Mutation spectrum revealed by breakpoint sequencing of human germline CNVs
    Conrad, Donald F.
    Bird, Christine
    Blackburne, Ben
    Lindsay, Sarah
    Mamanova, Lira
    Lee, Charles
    Turner, Daniel J.
    Hurles, Matthew E.
    NATURE GENETICS, 2010, 42 (05) : 385 - U43
  • [42] The impact of rare germline variants on human somatic mutation processes
    Vali-Pour, Mischan
    Lehner, Ben
    Supek, Fran
    NATURE COMMUNICATIONS, 2022, 13 (01)
  • [43] The Rate of Human Germline MutationsVariable Factor of Evolution and Diseases
    Uspenskaya, N. Y.
    Akopov, S. B.
    Snezhkov, E. V.
    Sverdlov, E. D.
    RUSSIAN JOURNAL OF GENETICS, 2019, 55 (05) : 523 - 534
  • [44] Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans
    Zoellner, S.
    Carlson, J.
    Li, J.
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2018, 26 : 77 - 77
  • [45] Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans
    Jedidiah Carlson
    Adam E. Locke
    Matthew Flickinger
    Matthew Zawistowski
    Shawn Levy
    Richard M. Myers
    Michael Boehnke
    Hyun Min Kang
    Laura J. Scott
    Jun Z. Li
    Sebastian Zöllner
    Nature Communications, 9
  • [46] p53 deficiency does not affect mutation rate in the mouse germline
    Burr, KLA
    Smith, AG
    Dubrova, YE
    ONCOGENE, 2005, 24 (26) : 4315 - 4318
  • [47] Low impact of germline transposition on the rate of mildly deleterious mutation in Caenorhabditis elegans
    Begin, Mattieu
    Schoen, Daniel J.
    GENETICS, 2006, 174 (04) : 2129 - 2136
  • [48] Experimental estimates of germline mutation rate in eukaryotes: a phylogenetic meta-analysis
    Wang, Yiguan
    Obbard, Darren J.
    EVOLUTION LETTERS, 2023, 7 (04) : 216 - 226
  • [49] Elevated germline mutation rate in teenage fathers (vol 282, 20142898, 2015)
    Forster, Peter
    Hohoff, Carsten
    Dunkelmann, Bettina
    Schurenkamp, Marianne
    Pfeiffer, Heidi
    Neuhuber, Franz
    Brinkmann, Bernd
    PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2016, 283 (1837)
  • [50] Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans
    Carlson, Jedidiah
    Locke, Adam E.
    Flickinger, Matthew
    Zawistowski, Matthew
    Levy, Shawn
    Myers, Richard M.
    Boehnke, Michael
    Kang, Hyun Min
    Scott, Laura J.
    Li, Jun Z.
    Zollner, Sebastian
    NATURE COMMUNICATIONS, 2018, 9
12345