A biology-aware mutation rate model for human germline

被引：0
|
作者：
Koch, Evan M. [1 ]
Seplyarskiy, Vladimir [1 ]
Sunyaev, Shamil R. [1 ]
机构：
[1] Harvard Med Sch, Dept Biomed Informat, Boston, MA 02115 USA
来源：
NATURE GENETICS | 2023年 / 55卷 / 12期
关键词：
D O I：
10.1038/s41588-023-01564-y
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
[No abstract available]
引用
收藏
页码：2033 / 2034
页数：2
相关论文
共 50 条
  • [31] BIOLOGICAL BASIS OF GERMLINE MUTATION - COMPARISONS OF SPONTANEOUS GERMLINE MUTATION-RATES AMONG DROSOPHILA, MOUSE, AND HUMAN
    DROST, JB
    LEE, WR
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 1995, 25 : 48 - 64
  • [32] Medical challenges for sequencing germline mutation in human disease
    Murakami, Yoshinori
    CANCER SCIENCE, 2018, 109 : 615 - 615
  • [33] Timing, Rates and Spectra of Human Germline Mutation.
    Lindsay, S. J.
    Rahbari, R.
    Kaplanis, J.
    Hurles, M. E.
    ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2020, 61 : 44 - 45
  • [34] HUMAN DISEASE Germline selection for deleterious mutation in males
    Casci, Tanita
    NATURE REVIEWS GENETICS, 2012, 13 (04) : 221 - 221
  • [35] Germline mutation rate is elevated in young and old parents in Caenorhabditis remanei
    Chen, Hwei-yen
    Krieg, Therese
    Mautz, Brian
    Jolly, Cecile
    Scofield, Douglas
    Maklakov, Alexei A.
    Immler, Simone
    EVOLUTION LETTERS, 2023, 7 (06) : 478 - 489
  • [36] Mutation rate in human microsatellites
    Henke, J
    Henke, L
    AMERICAN JOURNAL OF HUMAN GENETICS, 1999, 64 (05) : 1473 - 1473
  • [37] GENETICS The rate of human mutation
    Kondrashov, Alexey
    NATURE, 2012, 488 (7412) : 467 - 468
  • [38] Mutation spectrum revealed by breakpoint sequencing of human germline CNVs
    Donald F Conrad
    Christine Bird
    Ben Blackburne
    Sarah Lindsay
    Lira Mamanova
    Charles Lee
    Daniel J Turner
    Matthew E Hurles
    Nature Genetics, 2010, 42 : 385 - 391
  • [39] The impact of rare germline variants on human somatic mutation processes
    Mischan Vali-Pour
    Solip Park
    Jose Espinosa-Carrasco
    Daniel Ortiz-Martínez
    Ben Lehner
    Fran Supek
    Nature Communications, 13
  • [40] COMPLEX GENE CONVERSION EVENTS IN GERMLINE MUTATION AT HUMAN MINISATELLITES
    JEFFREYS, AJ
    TAMAKI, K
    MACLEOD, A
    MONCKTON, DG
    NEIL, DL
    ARMOUR, JAL
    NATURE GENETICS, 1994, 6 (02) : 136 - 145
12345