Gastric Carcinoma With Sebaceous Differentiation and SALL4 Expression

被引：0
|
作者：
Nakanishi, Takaaki [1 ]
Akita, Masayuki [2 ]
Ichikawa, Chihiro [1 ]
Kaneda, Kunihiko [2 ]
Tamura, Isamu [3 ]
Kawata, Yumiko [4 ]
Takahashi, Masayuki [5 ]
Imai, Yukihiro [1 ]
机构：
[1] Kakogawa Cent City Hosp, Dept Surg Pathol, Kakogawa, Japan
[2] Kakogawa Cent City Hosp, Dept Surg, Kakogawa, Japan
[3] Hyogo Prefectural Kakogawa Med Ctr, Div Gastroenterol, Kakogawa, Japan
[4] Kakogawa Cent City Hosp, Dept Dermatol, Kakogawa, Japan
[5] Kakogawa Cent City Hosp, Dept Otorhinolaryngol, Kakogawa, Japan
来源：
ACG CASE REPORTS JOURNAL | 2023年 / 10卷 / 05期
关键词：
stomach; AFP-producing adenocarcinoma; sebaceous carcinoma; SALL4;
D O I：
10.14309/crj.0000000000001061
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
A sebaceous carcinoma is rarely seen in extracutaneous sites. We present a 75-year-old man who was admitted with epigastralgia and melena. Endoscopic examination revealed an ulcer on the posterior wall of the gastric antrum, and distal gastrectomy was performed. Histopathological examination revealed thin to thick trabeculae of polygonal cells with scattered foci of foamy cells, whereas Sudan 3 staining showed lipid vacuoles. Immunohistochemistry was positive for both p40 and SALL4. After considering these findings, we suggest sebaceous differentiation as the diagnosis. To the best of our knowledge, this is the first case of gastric carcinoma with sebaceous differentiation.
引用
收藏
页数：4
相关论文
共 50 条
  • [31] Sall4 regulates differentiation and proliferation in hepatic stem/progenitor cells
    Oikowa, Tsunekazu
    Kamiya, Akihide
    Kakinuma, Sei
    Nishinakamura, Ryuichi
    Nakauchi, Hiromitsu
    HEPATOLOGY, 2007, 46 (04) : 322A - 322A
  • [32] Expression and clinical value of SALL4 in renal cell carcinomas
    Che, Jianping
    Wu, Pengfei
    Wang, Guangchun
    Yao, Xudong
    Zheng, Junhua
    Guo, Changcheng
    MOLECULAR MEDICINE REPORTS, 2020, 22 (02) : 819 - 827
  • [33] α-Fetoprotein-producing gastric carcinoma and combined hepatocellular and cholangiocarcinoma show similar morphology but different histogenesis with respect to SALL4 expression
    Ikeda, Hiroko
    Sato, Yasunori
    Yoneda, Norihide
    Harada, Kenichi
    Sasaki, Motoko
    Kitamura, Seiko
    Sudo, Yoshiko
    Ooi, Akishi
    Nakanuma, Yasuni
    HUMAN PATHOLOGY, 2012, 43 (11) : 1955 - 1963
  • [34] Expression and clinical significance of SALL4 and β-catenin in colorectal cancer
    Liliang Hao
    Yan Zhao
    Zhen Wang
    Hongzhuan Yin
    Xin Zhang
    Tao He
    Shanshan Song
    Shaolong Sun
    Baosheng Wang
    Zhijie Li
    Qi Su
    Journal of Molecular Histology, 2016, 47 : 117 - 128
  • [35] Potential application of human SALL4 on oral squamous cell carcinoma
    Matos, Leandro Luongo
    da Silva, Jessical Boscariol
    ANNALS OF TRANSLATIONAL MEDICINE, 2022, 10 (17)
  • [36] Immunohistochemical expression of SALL4 in hepatocellular carcinoma, a potential pitfall in the differential diagnosis of yolk sac tumors
    Gonzalez-Roibon, Nilda
    Katz, Betina
    Chaux, Alcides
    Sharma, Rajni
    Munari, Enrico
    Faraj, Sheila F.
    Illei, Peter B.
    Torbenson, Michael
    Netto, George J.
    HUMAN PATHOLOGY, 2013, 44 (07) : 1293 - 1299
  • [37] The SALL4 gene in acute leukemias
    Abo-Elwafa, Hasnaa A.
    Aziz, Shereen P.
    Salah, Maged M.
    Sedek, Osamah B.
    EGYPTIAN JOURNAL OF HAEMATOLOGY, 2015, 40 (03): : 121 - 129
  • [38] Immunohistochemical Expression of SALL4 in Hepatocellular Carcinoma, a Potential Pitfall in the Differential Diagnosis of Yolk Sac Tumors
    Katz, B.
    Gonzalez-Roibon, N. D.
    Chaux, A.
    Sharma, R.
    Netto, G. J.
    Torbenson, M.
    LABORATORY INVESTIGATION, 2012, 92 : 217A - 217A
  • [39] SALL4: Engine of Cell Stemness
    Xiong, Jianhua
    CURRENT GENE THERAPY, 2014, 14 (05) : 400 - 411
  • [40] SALL4—a cancer marker and target
    Bryony Jones
    Nature Reviews Clinical Oncology, 2013, 10 (8) : 426 - 426
12345