Inherently chiral azaheterocycles: Asymmetric synthesis via (dynamic) kinetic resolution

被引：0
|
作者：
Luo, Yu [1 ,2 ]
Luo, Shuang [1 ,2 ]
Zhu, Qiang [1 ,2 ]
机构：
[1] Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, State Key Lab Resp Dis, 190 Kaiyuan Ave, Guangzhou 510530, Peoples R China
[2] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China
来源：
CHEM CATALYSIS | 2024年 / 4卷 / 01期
基金：
中国博士后科学基金; 中国国家自然科学基金;
关键词：
D O I：
10.1016/j.checat.2023.100864
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
In this issue of Chem Catalysis, Yang et al. presented methods for the synthesis of enantioenriched inherently chiral 9,10-dihydrotribenzo[b,d,f]azocines through kinetic resolution (KR) and dynamic kinetic resolution (DKR). Chiral phosphoric acid catalyzed C-H amination and transferred hydrogenation from racemic precursors, yielding inherently chiral saddle -shaped eight -membered azaheterocycles enantioselectively under mild conditions.
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页数：3
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