Sonic hedgehog signaling during nervous system development

被引：0
|
作者：
Qin Yang
机构：
来源：
Neural Regeneration Research | 2008年 / 07期
关键词：
development; nervous system; review; Sonic hedgehog;
D O I：
暂无
中图分类号：
R741 [神经病学];
学科分类号：
摘要：
The Hedgehog signaling pathway plays a key role in embryonic development and organ formation. Sonic hedgehog signaling participates in nervous system development, regulates proliferation and differentiation of neural stem cells, controls growth and targeting of axons, and contributes to specialization of oligodendrocytes. For further studies of the Sonic hedgehog signaling pathway and for the development of new drugs in the treatment of nervous system diseases, it is beneficial to understand these mechanisms.
引用
收藏
页码：782 / 785
页数：4
相关论文
共 50 条
  • [41] Sonic Hedgehog Signaling Is a Positive Oligodendrocyte Regulator during Demyelination
    Ferent, Julien
    Zimmer, Celine
    Durbec, Pascale
    Ruat, Martial
    Traiffort, Elisabeth
    JOURNAL OF NEUROSCIENCE, 2013, 33 (05): : 1759 - 1772
  • [42] Sonic hedgehog, the penis and erectile dysfunction: A review of sonic hedgehog signaling in the penis
    Podlasek, CA
    Meroz, CL
    Korolis, H
    Tang, Y
    McKenna, KE
    McVary, KT
    CURRENT PHARMACEUTICAL DESIGN, 2005, 11 (31) : 4011 - 4027
  • [43] Immunohistochemical Characterization of Sonic Hedgehog and its Downstream Signaling Molecules During Human Penile Development
    Shehata, Bahig M.
    Elmore, James M.
    Bootwala, Yasmin
    Steelman, Charlotte K.
    Bare, Jessica B.
    Shoffeitt, Carla J.
    Wang, Ruoxiang
    Zhau, Haiyen E.
    He, Dalin
    Zhu, Guodong
    Chung, Leland W.
    FETAL AND PEDIATRIC PATHOLOGY, 2011, 30 (04) : 244 - 251
  • [44] A novel role for cilia-dependent sonic hedgehog signaling during submandibular gland development
    Elliott, Kelsey H.
    Millington, Grethel
    Brugmann, Samantha A.
    DEVELOPMENTAL DYNAMICS, 2018, 247 (06) : 818 - 831
  • [45] Development of stratum intermedium and its role as a Sonic hedgehog-signaling structure during odontogenesis
    Koyama, E
    Wu, CS
    Shimo, T
    Iwamoto, M
    Ohmori, T
    Kurisu, K
    Ookura, T
    Bashir, MM
    Abrams, WR
    Tucker, T
    Pacifici, M
    DEVELOPMENTAL DYNAMICS, 2001, 222 (02) : 178 - 191
  • [46] Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development
    Zhan, Xiaoming
    Shi, Xuanming
    Zhang, Zilai
    Chen, Yu
    Wu, Jiang I.
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (31) : 12758 - 12763
  • [47] The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease
    Parkin, Caroline A.
    Ingham, Philip W.
    AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2008, 294 (02): : G363 - G367
  • [48] Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling
    Petrova E.
    Rios-Esteves J.
    Ouerfelli O.
    Glickman J.F.
    Resh M.D.
    Nature Chemical Biology, 2013, 9 (4) : 247 - 249
  • [49] Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling
    Petrova, Elissaveta
    Rios-Esteves, Jessica
    Ouerfelli, Ouathek
    Glickman, J. Fraser
    Resh, Marilyn D.
    NATURE CHEMICAL BIOLOGY, 2013, 9 (04) : 247 - 249
  • [50] The Role of Sonic Hedgehog Pathway in the Development of the Central Nervous System and Aging-Related Neurodegenerative Diseases
    Yang, Chen
    Qi, Yan
    Sun, Zhitang
    FRONTIERS IN MOLECULAR BIOSCIENCES, 2021, 8
12345