Sonic hedgehog signaling during nervous system development

被引:0
|
作者
Qin Yang
机构
关键词
development; nervous system; review; Sonic hedgehog;
D O I
暂无
中图分类号
R741 [神经病学];
学科分类号
摘要
The Hedgehog signaling pathway plays a key role in embryonic development and organ formation. Sonic hedgehog signaling participates in nervous system development, regulates proliferation and differentiation of neural stem cells, controls growth and targeting of axons, and contributes to specialization of oligodendrocytes. For further studies of the Sonic hedgehog signaling pathway and for the development of new drugs in the treatment of nervous system diseases, it is beneficial to understand these mechanisms.
引用
收藏
页码:782 / 785
页数:4
相关论文
共 50 条
  • [21] The transcriptional repressor REST regulates Sonic Hedgehog signaling during zebrafish development
    Gates, Keith P.
    Mentzer, Laura
    Sirotkin, Howard I.
    DEVELOPMENTAL BIOLOGY, 2008, 319 (02) : 570 - 570
  • [22] Sonic Hedgehog Signaling in the Lung From Development to Disease
    Kugler, Matthias C.
    Joyner, Alexandra L.
    Loomis, Cynthia A.
    Munger, John S.
    AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 2015, 52 (01) : 1 - 13
  • [23] SONIC HEDGEHOG SIGNALING IN NORMAL HUMAN BLADDER DEVELOPMENT
    Zhu, Guodong
    Zhau, Haiyen
    Wu, Dapeng
    Song, Wenbin
    He, Dalin
    Chung, Leland
    JOURNAL OF UROLOGY, 2016, 195 (04): : E412 - E412
  • [24] SONIC HEDGEHOG SIGNALING IN NORMAL HUMAN BLADDER DEVELOPMENT
    Zhu, Guodong
    Zhau, Haiyen E.
    Wu, Dapeng
    Zhang, Linlin
    Li, Lei
    He, Dalin
    Chung, Leland W. K.
    JOURNAL OF UROLOGY, 2013, 189 (04): : E222 - E222
  • [25] Development of taladegib as a sonic hedgehog signaling pathway inhibitor
    Guanghai Jin
    Aneesh Sivaraman
    Kyeong Lee
    Archives of Pharmacal Research, 2017, 40 : 1390 - 1393
  • [26] Sonic hedgehog signaling is important in tooth root development
    Nakatomi, M
    Morita, I
    Eto, K
    Ota, MS
    JOURNAL OF DENTAL RESEARCH, 2006, 85 (05) : 427 - 431
  • [27] Sonic hedgehog signaling is essential for salivary gland development
    Jaskoll, T
    Leo, T
    Carlsson, P
    Ormestad, M
    Astorga, J
    Zhou, Y
    Melnick, M
    MOLECULAR BIOLOGY OF THE CELL, 2002, 13 : 256A - 256A
  • [28] The roles of Sonic hedgehog signaling in development of mammalian neocortex
    Ishibashi, Makoto
    Komada, Munekazu
    Saitsu, Hirotomo
    Kinoshi, Masato
    Miura, Takashi
    Shiota, Kohei
    NEUROSCIENCE RESEARCH, 2008, 61 : S227 - S227
  • [29] Development of taladegib as a sonic hedgehog signaling pathway inhibitor
    Jin, Guanghai
    Sivaraman, Aneesh
    Lee, Kyeong
    ARCHIVES OF PHARMACAL RESEARCH, 2017, 40 (12) : 1390 - 1393
  • [30] The Sonic hedgehog signaling system as a bistable genetic switch
    Lai, K
    Robertson, MJ
    Schaffer, DV
    BIOPHYSICAL JOURNAL, 2004, 86 (05) : 2748 - 2757