Overcoming multidrug resistance(MDR) in cancer by nanotechnology

被引：0
|
作者：
BU HuiHui
机构：
来源：
Science China Chemistry | 2010年 / 53卷 / 11期
基金：
中国国家自然科学基金;
关键词：
nanotechnology; nanoparticles; multidrug resistance; chemotherapeutic drugs; cancer; drug delivery system;
D O I：
暂无
中图分类号：
R319 [其他科学技术在医学上的应用];
学科分类号：
1001 ;
摘要：
The emerging nanotechnology-based drug delivery holds tremendous potential to deliver chemotherapeutic drugs for treatment of multidrug resistance(MDR) cancer.This drug delivery system could improve the pharmacokinetic behavior of antitumor drugs,deliver chemotherapeutic drugs to target sites,control release of drugs,and reduce the systemic toxicity of drugs in MDR cancer.This review addresses the use of nanotechnology to overcome MDR classified on the bases of the fundamental mechanisms of MDR and various approaches to deliver drugs for treatment of MDR cancer.
引用
收藏
页码：2226 / 2232
页数：7
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