A Novel Reductive Cyclization of o-Nitrobenzamides and Ketones Promoted by Low-valent Titanium Reagent

被引：0
|
作者：
史达清
荣良策
王菊仙
庄启亚
屠树江
机构：
[1] Department of Chemistry
[2] Xuzhou Normal University
[3] Jiangsu 221116
[4] China The Key Laboratory of Biotechnology on Medical Plant of Jiangsu Province
[5] China
来源：
ChineseJournalofChemistry | 2004年 / 07期
关键词：
quinazolin-4(3H)-one; low-valent titanium; o-nitrobenzamide;
D O I：
暂无
中图分类号：
O621 [有机化学一般性问题];
学科分类号：
摘要：
A short and facile synthesis of a series of 1,2-dihydroquiazolin-4(3H)-ones was accomplished in good yields via novel reductive cyclization of o-nitrobenzamides with ketones promoted by TiCl4/Zn system. The structure was established on the basis of elemental analysis, IR, 1H NMR and confirmed by a single-crystal X-ray diffraction analysis. This method has the advantages of easily accessible starting materials, convenient manipulation and moderate to high yields.
引用
收藏
页码：743 / 746 +616
页数：5
相关论文
共 50 条
  • [31] Low-valent titanium induced reductive cyclization of (3-oxo-1,3-diaryl) propylpropanedinitrile
    Shi, DQ
    Tu, SJ
    Zhou, LH
    Feng, YJ
    Dai, GY
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 1998, 19 (02): : 237 - 242
  • [32] REDUCTIVE PROPERTIES OF LOW-VALENT TITANIUM REAGENTS - MECHANISTIC STUDIES
    MALINOWSKI, M
    KACZMAREK, L
    ROZPLOCH, F
    JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1991, (06): : 879 - 883
  • [33] LOW-VALENT TITANIUM INDUCED REDUCTIVE CROSS-COUPLING REACTION OF ACYL CHLORIDES WITH DIARYL KETONES
    Da Qing SHI Department of Chemistry
    ChineseChemicalLetters, 1993, (08) : 681 - 682
  • [34] LOW-VALENT TITANIUM INDUCED REDUCTIVE REACTION OF THIOCYANATES AND ISOCYANATE
    Jian Xie CHEN
    ChineseChemicalLetters, 1993, (11) : 943 - 946
  • [35] REDUCTIVE ELIMINATION PATHWAYS TO LOW-VALENT TITANIUM ARYLOXIDE COMPLEXES
    DURFEE, LD
    FANWICK, PE
    ROTHWELL, IP
    FOLTING, K
    HUFFMAN, JC
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (15) : 4720 - 4722
  • [36] REDUCTIVE COUPLINGS OF KETONES BY LOW-VALENT TITANIUM, PREPARED FROM TICL4 AND REDUCING AGENTS
    DAMS, R
    MALINOWSKI, M
    GEISE, HJ
    BULLETIN DES SOCIETES CHIMIQUES BELGES, 1981, 90 (11): : 1141 - 1152
  • [37] Low-valent titanium reductive coupling reactions of pyrrylaldehydes and pyrrylketones
    Cheng, JM
    Gano, JE
    Morgan, AR
    TETRAHEDRON LETTERS, 1996, 37 (16) : 2721 - 2724
  • [38] A novel cyclodimerization of alpha beta-unsaturated ketones induced by low-valent titanium
    Zhou, LH
    Shi, DQ
    Gao, Y
    Shen, WB
    Dai, GY
    Chen, WX
    TETRAHEDRON LETTERS, 1997, 38 (15) : 2729 - 2732
  • [39] Reductive amination of aliphatic carbonyls using low-valent titanium reagent: a convenient route to free primary amines
    Rele, S
    Banerji, A
    Talukdar, S
    JOURNAL OF CHEMICAL RESEARCH, 2002, (06) : 253 - 254
  • [40] Reductive dehydroxylation of Baylis-Hillman adducts with low-valent titanium reagent: syntheses of stereoselective trisubstituted alkenes
    Shadakshari, U
    Nayak, SK
    TETRAHEDRON, 2001, 57 (21) : 4599 - 4602
12345