A Novel Reductive Cyclization of o-Nitrobenzamides and Ketones Promoted by Low-valent Titanium Reagent

被引：0

作者：

史达清

荣良策

王菊仙

庄启亚

屠树江

机构：

[1] Department of Chemistry

[2] Xuzhou Normal University

[3] Jiangsu 221116

[4] China The Key Laboratory of Biotechnology on Medical Plant of Jiangsu Province

[5] China

来源：

ChineseJournalofChemistry | 2004年 / 07期

关键词：

quinazolin-4(3H)-one; low-valent titanium; o-nitrobenzamide;

D O I：

暂无

中图分类号：

O621 [有机化学一般性问题];

学科分类号：

摘要：

A short and facile synthesis of a series of 1,2-dihydroquiazolin-4(3H)-ones was accomplished in good yields via novel reductive cyclization of o-nitrobenzamides with ketones promoted by TiCl4/Zn system. The structure was established on the basis of elemental analysis, IR, 1H NMR and confirmed by a single-crystal X-ray diffraction analysis. This method has the advantages of easily accessible starting materials, convenient manipulation and moderate to high yields.

引用

页码：743 / 746 +616

页数：5

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