L-Proline catalyzed one-pot multi-component synthesis of 2-(1,3-diphenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one derivatives and their biological studies

被引：0
|
作者：
Hemal B. Mehta [1 ]
Bharat C. Dixit [2 ]
Ritu B. Dixit [1 ]
机构：
[1] Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences
[2] Chemistry Departments,V P and R P T P Science College,Affiliated to Sardar Patel
来源：
ChineseChemicalLetters | 2014年 / 25卷 / 05期
关键词：
D O I：
暂无
中图分类号：
TQ465 [抗菌素制造];
学科分类号：
100705 ;
摘要：
A new series of quinazolin-4(3H)-one derivatives containing a(1 3-diphenyl-1H-pyrazol-4-yl) core with substituents at the 2-position and aromatic or heteroaromatic substituents at the 3-position were synthesized using an L-proline catalyzed one-pot multi-component reaction approach.All the synthesized compounds were characterized and screened for their antimicrobial,antifungal and anti-tubercular activities.
引用
收藏
页码：741 / 744
页数：4
相关论文
共 50 条
  • [21] Synthesis, Spectral, and Computational Studies of 2-Cyano-3-(1,3-diphenyl-1H-pyrazol-4-yl)acrylamide
    Iniyaval, Shunmugam
    Krishnan, Kannan Gokula
    Malathi, Shanmugam
    Ramalingan, Chennan
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2023, 33 (02) : 257 - 269
  • [22] Gallium(III) triflate-catalyzed one-pot selective synthesis of 2 3-dihydroquinazolin-4(1H)-ones and quinazolin-4(3H)-ones
    Chen, Jiuxi
    Wu, Dengze
    He, Fei
    Liu, Miaochang
    Wu, Huayue
    Ding, Jinchang
    Su, Weike
    TETRAHEDRON LETTERS, 2008, 49 (23) : 3814 - 3818
  • [23] Clean heterocyclic synthesis in water:I2/KI catalyzed one-pot synthesis of quinazolin-4(3H)-ones
    Mehdi Bakavoli
    Ali Shiri
    Zahra Ebrahimpour
    Mohammad Rahimizadeh
    ChineseChemicalLetters, 2008, 19 (12) : 1403 - 1406
  • [24] Clean heterocyclic synthesis in water: I2/KI catalyzed one-pot synthesis of quinazolin-4(3H)-ones
    Bakavoli, Mehdi
    Shiri, Ali
    Ebrahimpour, Zahra
    Rahimizadeh, Mohammad
    CHINESE CHEMICAL LETTERS, 2008, 19 (12) : 1403 - 1406
  • [25] Synthesis and Anticonvulsant Activity of Some Quinazolin-4(3H)-one Derivatives
    Georgey, Hanan
    Abdel-Gawad, Nagwa
    Abbas, Safinaz
    MOLECULES, 2008, 13 (10): : 2557 - 2569
  • [26] Synthesis and Antifungal Activity of Novel Quinazolin-4(3H)-one Derivatives
    El-Hashash, Maher A.
    Elshahawi, Manal M.
    Ragab, Eman A.
    Nagdy, Sanaa
    SYNTHETIC COMMUNICATIONS, 2015, 45 (19) : 2240 - 2250
  • [27] Synthesis and Immunotropic Activity of Quinazolin-4(3H)-One Carbonyl Derivatives
    Samotrueva, M. A.
    Tsibizova, A. A.
    Ozerov, A. A.
    Luzhnova, S. A.
    Glukhova, E. G.
    Tyurenkov, I. N.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2016, 50 (06) : 362 - 364
  • [28] One-pot synthesis of quinazolin-4(3H)-ones and fused quinazolinones by a palladium-catalyzed domino process
    Ren, Zhi-Lin
    Kong, Han-Han
    Lu, Wen-Ting
    Sun, Mei
    Ding, Ming-Wu
    TETRAHEDRON, 2018, 74 (01) : 184 - 193
  • [29] Synthesis and antimicrobial activity of polyhalobenzonitrile quinazolin-4(3H)-one derivatives
    Shi, Li-Ping
    Jiang, Kun-Ming
    Jiang, Jun-Jie
    Jin, Yi
    Tao, Yun-Hai
    Li, Ke
    Wang, Xing-Hong
    Lin, Jun
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (21) : 5958 - 5963
  • [30] Synthesis and Immunotropic Activity of Quinazolin-4(3H)-One Carbonyl Derivatives
    M. A. Samotrueva
    A. A. Tsibizova
    A. A. Ozerov
    S. A. Luzhnova
    E. G. Glukhova
    I. N. Tyurenkov
    Pharmaceutical Chemistry Journal, 2016, 50 : 362 - 364
12345