Expression of Apoptosis Related Protein in Skin Lesions of Lichen Planus and Its Implication

被引：0

作者：

陈旭娥

吴艳

李家文

刘志香

岳青

刘厚君

机构：

[1] Wuhan 430022

[2] China

[3] Department of Dermatology Union Hospital

[4] Huazhong University of Science and Technology

[5] Tongji Medical College

来源：

Journal of Huazhong University of Science and Technology(Medical Sciences) | 2008年 / 03期

关键词：

Caspase-3; Bax; lichen planus;

D O I：

暂无

中图分类号：

R758.65 [扁平苔癣];

学科分类号：

摘要：

In order to investigate the role of Caspase-3 and Bax in the pathogenesis of lichen planus,immunohistochemistry was used to detect the expression of Caspase-3 and Bax in skin lesions of the patients with lichen planus and skin tissues of normal subjects.The results showed that positive rate of Caspase-3 and Bax expression in lichen planus were significantly higher than that in normal skins(both P<0.05).Meanwhile,there was a obvious correlation between the increase of Caspase-3 and that of Bax in lichen planus.The expression of Caspase-3 and Bax might play an important role in the development of lichen planus.

引用

页码：349 / 351

页数：3

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