Expression of Apoptosis Related Protein in Skin Lesions of Lichen Planus and Its Implication

被引：0
|
作者：
陈旭娥
吴艳
李家文
刘志香
岳青
刘厚君
机构：
[1] Wuhan 430022
[2] China
[3] Department of Dermatology Union Hospital
[4] Huazhong University of Science and Technology
[5] Tongji Medical College
来源：
Journal of Huazhong University of Science and Technology(Medical Sciences) | 2008年 / 03期
关键词：
Caspase-3; Bax; lichen planus;
D O I：
暂无
中图分类号：
R758.65 [扁平苔癣];
学科分类号：
摘要：
In order to investigate the role of Caspase-3 and Bax in the pathogenesis of lichen planus,immunohistochemistry was used to detect the expression of Caspase-3 and Bax in skin lesions of the patients with lichen planus and skin tissues of normal subjects.The results showed that positive rate of Caspase-3 and Bax expression in lichen planus were significantly higher than that in normal skins(both P<0.05).Meanwhile,there was a obvious correlation between the increase of Caspase-3 and that of Bax in lichen planus.The expression of Caspase-3 and Bax might play an important role in the development of lichen planus.
引用
收藏
页码：349 / 351
页数：3
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