Study of Analgesic and Anti-inflammatory Effects of Lappaconitine Gelata

被引：0
|
作者：
王英姿 [1 ]
肖勇庆 [2 ]
张超 [3 ]
孙秀梅 [3 ]
机构：
[1] College of Chinese Materia Medica, Beijing University of Traditional Chinese Medicine,Beijing 100102, China
[2] China Academy of Traditional Chinese Medicine,Beijing 100700, China
[3] College of Pharmacy, Shandong University of Traditional Chinese Medicine,Jinan 250014, China
来源：
JournalofTraditionalChineseMedicine | 2009年 / 29卷 / 02期
关键词：
lappaconitine gelata; pharmacodynamics; analgesic effect; anti-inflammatory effect; animal test;
D O I：
暂无
中图分类号：
R285.5 [中药实验药理];
学科分类号：
1008 ;
摘要：
Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA). Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in the mouse, and the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were used for investigation on the analgesic and anti-inflammatory effects of LA. Results: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate methods was significantly inhibited by LA. In addition, the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were all significantly suppressed by LA. Conclusion: LA has the analgesic and anti-inflammatory effects.
引用
收藏
页码：141 / 145
页数：5
相关论文
共 50 条
  • [31] Analgesic and Anti-Inflammatory Effects of an Extract of Fadogia agrestis in Rats
    Oyekunle, O. A.
    Okojie, A. K.
    Udoh, U. S.
    NEUROPHYSIOLOGY, 2010, 42 (02) : 124 - 129
  • [32] Analgesic and anti-inflammatory effects of honey: the involvement of autonomic receptors
    Owoyele, Bamidele Victor
    Oladejo, Rasheed Olajiire
    Ajomale, Kayode
    Ahmed, Rasheedat Omotayo
    Mustapha, Abdulrasheed
    METABOLIC BRAIN DISEASE, 2014, 29 (01) : 167 - 173
  • [33] ANTI-INFLAMMATORY AND ANALGESIC EFFECTS OF ELEUTHEROSIDE E IN ALCOHOLIC BEVERAGE
    Liu, Y. C.
    Yang, Y. J.
    Chen, M. S.
    Wang, Z.
    Chen, Y. H.
    Zhang, Y. F.
    Shan, Y. M.
    Yu, B.
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2019, 33 (06): : 1815 - 1821
  • [34] Evaluation of Antipyretic, Analgesic and Anti-inflammatory Effects of Nimesulide Injection
    Wang, C. Y.
    Wu, M. W.
    Bourkaib, Nadia
    Luo, Y. H.
    Chen, Q.
    Zhu, J.
    Dong, X. R.
    Feng, H. X.
    LATIN AMERICAN JOURNAL OF PHARMACY, 2012, 31 (10): : 1412 - 1416
  • [35] Evaluation of the Antipyretic, Analgesic, and Anti-inflammatory Effects of Pregabalin in Chicks
    Bashar, Qutaiba M.
    Albadrany, Yasser M.
    EGYPTIAN JOURNAL OF VETERINARY SCIENCE, 2022, 53 (03): : 323 - 328
  • [36] Evaluation of Anti-inflammatory and Analgesic Effects of Synthesized Derivatives of Ibuprofen
    Wang, Jingjie
    Dai, Dongyan
    Qiu, Qianqian
    Deng, Xin
    Lin, Haiyan
    Qian, Hai
    Huang, Wenlong
    CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 85 (05) : 623 - 632
  • [37] Anti-inflammatory, Analgesic, and Cytotoxic Effects of The Phytexponent: A Polyherbal Formulation
    Odira, Halvince O.
    Mitema, Simon O.
    Mapenay, Isaac M.
    Moriasi, Gervason A.
    JOURNAL OF EVIDENCE-BASED INTEGRATIVE MEDICINE, 2022, 27
  • [38] Analgesic effects and anti-inflammatory mechanism of dragonn's blood
    Li, Yu-Sang
    Liu, Min
    Wang, Jun-Xian
    Pei, Lan-Jie
    Jia, Meimei
    Tang, He-Bin
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2011, 115 : 280P - 280P
  • [39] Anti-inflammatory, analgesic and acute toxicity effects of fermented soybean
    Yusof, Hamidah Mohd
    Ali, Norlaily Mohd
    Yeap, Swee Keong
    Ho, Wan Yong
    Beh, Boon Kee
    Koh, Soo Peng
    Long, Kamariah
    Alitheen, Noorjahan Banu
    BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2019, 19 (01):
  • [40] Analgesic and anti-inflammatory effects of Pistacia integerrima extracts in mice
    Ahmad, Naseem Saud
    Waheed, Akbar
    Farman, Muhammad
    Qayyum, Aisha
    JOURNAL OF ETHNOPHARMACOLOGY, 2010, 129 (02) : 250 - 253
12345