Study of Analgesic and Anti-inflammatory Effects of Lappaconitine Gelata

被引：0
|
作者：
王英姿 [1 ]
肖勇庆 [2 ]
张超 [3 ]
孙秀梅 [3 ]
机构：
[1] College of Chinese Materia Medica, Beijing University of Traditional Chinese Medicine,Beijing 100102, China
[2] China Academy of Traditional Chinese Medicine,Beijing 100700, China
[3] College of Pharmacy, Shandong University of Traditional Chinese Medicine,Jinan 250014, China
来源：
JournalofTraditionalChineseMedicine | 2009年 / 29卷 / 02期
关键词：
lappaconitine gelata; pharmacodynamics; analgesic effect; anti-inflammatory effect; animal test;
D O I：
暂无
中图分类号：
R285.5 [中药实验药理];
学科分类号：
1008 ;
摘要：
Objective: To explore the analgesic and anti-inflammatory effects of lappaconitine gelata (LA). Methods: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate method in the mouse, and the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were used for investigation on the analgesic and anti-inflammatory effects of LA. Results: The writhing response induced by acetic acid, the pain response induced by formaldehyde and hot plate methods was significantly inhibited by LA. In addition, the paw edema induced by egg albumen in the rat and the ear edema induced by xylene in the mouse were all significantly suppressed by LA. Conclusion: LA has the analgesic and anti-inflammatory effects.
引用
收藏
页码：141 / 145
页数：5
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