Expression of transforming growth factor beta-1 in fibrosis of transplanted kidney

被引:1
|
作者
崔飞伦
孙颖浩
彭瑞云
高亚兵
王德文
机构
[1] The affiliated First People’s Hospital of Jiangsu University
[2] Changhai Hospital
[3] Beijing 100850
[4] China
[5] Department of Urology
[6] Institute of Radiation Medicine
[7] Zhenjiang 212002
[8] Academy of Military Medical Science
[9] Second Military Medical University
[10] Shanghai 200433
关键词
TGF-β1; molecular pathogenic mechanism; transplanted renal fibrosis;
D O I
暂无
中图分类号
R699.2 [肾脏手术];
学科分类号
摘要
Objective: In order to study the role and significance of transforming growth factor beta-1 (TGF-β1 )mRNA in transplanted renal fibrosis(TRF). Methods: Renal pathologic changes and expression of TGF-β1 mRNA were observed using in situ hybridization technique. The normal renal tissue as a. control group. Results: Expression of TGF-β1, mRNA in the renal fibrosis increased, compared with that in the control group. The expression rate were co-related to the stage of TRF. Conclusion: TGF-β1 is related to the pathogenesis and development of TRF.
引用
收藏
页码:357 / 358
页数:2
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