Expression of transforming growth factor beta-1 in fibrosis of transplanted kidney

被引：1
|
作者：
崔飞伦
孙颖浩
彭瑞云
高亚兵
王德文
机构：
[1] The affiliated First People’s Hospital of Jiangsu University
[2] Changhai Hospital
[3] Beijing 100850
[4] China
[5] Department of Urology
[6] Institute of Radiation Medicine
[7] Zhenjiang 212002
[8] Academy of Military Medical Science
[9] Second Military Medical University
[10] Shanghai 200433
来源：
Journal of Medical Colleges of PLA | 2004年 / 06期
关键词：
TGF-β1; molecular pathogenic mechanism; transplanted renal fibrosis;
D O I：
暂无
中图分类号：
R699.2 [肾脏手术];
学科分类号：
摘要：
Objective: In order to study the role and significance of transforming growth factor beta-1 (TGF-β1 )mRNA in transplanted renal fibrosis(TRF). Methods: Renal pathologic changes and expression of TGF-β1 mRNA were observed using in situ hybridization technique. The normal renal tissue as a. control group. Results: Expression of TGF-β1, mRNA in the renal fibrosis increased, compared with that in the control group. The expression rate were co-related to the stage of TRF. Conclusion: TGF-β1 is related to the pathogenesis and development of TRF.
引用
收藏
页码：357 / 358
页数：2
相关论文
共 50 条
  • [11] Peritoneal transforming growth factor beta-1 expression during laparoscopic surgery: A clinical trial
    Brokelman W.J.A.
    Holmdahl L.
    Bergström M.
    Falk P.
    Klinkonbijl J.H.G.
    Reijnen M.M.P.J.
    Surgical Endoscopy, 2007, 21 (9) : 1537 - 1541
  • [12] Peritoneal transforming growth factor beta-1 expression during laparoscopic surgery: a clinical trial
    Walter J. A. Brokelman
    Lena Holmdahl
    Maria Bergström
    Peter Falk
    Jean H. G. Klinkenbijl
    Michel M. P. J. Reijnen
    Surgical Endoscopy, 2007, 21 : 1542 - 1542
  • [13] Immunohistochemical Expression of Interleukin-6 and Transforming Growth Factor Beta-1 on Prostatic Lesions
    Abdulrazaq, Alaa Abdulqader
    Abdulkareem, Duraid Taha
    INDIAN JOURNAL OF SURGICAL ONCOLOGY, 2025,
  • [14] COORDINATED EXPRESSION OF BETA-1 INTEGRINS AND TRANSFORMING GROWTH FACTOR-BETA-INDUCED MATRIX PROTEINS IN GLOMERULONEPHRITIS
    KAGAMI, S
    BORDER, WA
    RUOSLAHTI, E
    NOBLE, NA
    LABORATORY INVESTIGATION, 1993, 69 (01) : 68 - 76
  • [15] Overexpression of transforming growth factor beta-1 (TGF-B1) is associated with reduced PTEN expression in pancreatic fibrosis and cancer.
    Ebert, M
    Fei, G
    Herrera, P
    Friess, H
    Buechler, M
    Malfertheiner, P
    GASTROENTEROLOGY, 2000, 118 (04) : A650 - A650
  • [16] Transforming Growth Factor Beta-1 in Acute Myocardial Infarction in Rats
    Thompson, Nancy L.
    Bazoberry, Fernando
    Speir, Edith H.
    Casscells, Ward
    Ferrans, Victor J.
    Flanders, Kathleen C.
    Kondaiah, Patljru
    Geiser, Andrew G.
    Sporn, Michael B.
    GROWTH FACTORS, 1988, 1 (01) : 91 - 99
  • [17] Gastric lesions in transforming growth factor beta-1 heterozygous mice
    Boivin, GP
    Molina, JR
    Ormsby, I
    Stemmermann, G
    Doetschman, T
    LABORATORY INVESTIGATION, 1996, 74 (02) : 513 - 518
  • [18] TRANSFORMING GROWTH FACTOR BETA-1 GENE POLYMORPHISMS AND ANKYLOSING SPONDYLITIS
    Jaakkola, E.
    Herzberg-Wallbank, I.
    Sims, A-M
    Bradbury, L.
    Calin, A.
    Laiho, K.
    Crane, A.
    Wordsworth, P.
    Tuomilehto, J.
    Brown, M.
    RHEUMATOLOGY, 2003, 42 : 81 - 82
  • [19] Laminin and transforming growth factor beta-1 in children with vesicoureteric reflux
    Anna Sabasiñska
    Walentyna Zoch-Zwierz
    Anna Wasilewska
    Tadeusz Porowski
    Pediatric Nephrology, 2008, 23 : 769 - 774
  • [20] Immunohistochemical localization of transforming growth factor beta-1 and its relationship with collagen expression in advanced liver fibrosis due to biliary atresia
    Farrington, Christian
    Novak, Don
    Liu, Chen
    Haafiz, Allah B.
    CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY, 2010, 3 : 185 - 191
12345