A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media

被引：1
|
作者：
Robabeh Baharfar [1 ]
Razieh Azimi [1 ]
机构：
[1] Faculty of Chemistry,Mazandaran University,Babolsar,Iran
来源：
ChineseChemicalLetters | 2011年 / 22卷 / 10期
关键词：
Pyrido[2,3-d]pyrimidine; 6-Aminothiouracil; Diethyl ethoxymethylenemalonate; α; β-Unsaturated carbonyl compounds;
D O I：
暂无
中图分类号：
O626.41 [间（二）氮苯（嘧啶）族];
学科分类号：
摘要：
A series of pyrido[2,3-d]pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6- aminothiouracil withα,β-unsaturated carbonyl compounds（aldehyde,ketone and ester） possessing a leaving group on theβposition,in H;O under reflux conditions.
引用
收藏
页码：1183 / 1186
页数：4
相关论文
共 50 条
  • [41] An efficient synthesis of pyrido[2,3-d]pyrimidine derivatives and related compounds under ultrasound irradiation without catalyst
    Tu, Shujiang
    Cao, Longji
    Zhang, Yan
    Shao, Qingqing
    Zhou, Dianxiang
    Li, Chunmei
    ULTRASONICS SONOCHEMISTRY, 2008, 15 (03) : 217 - 221
  • [42] Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity
    Kurumurthy, C.
    Rao, P. Sambasiva
    Swamy, B. Veera
    Kumar, G. Santhosh
    Rao, P. Shanthan
    Narsaiah, B.
    Velatooru, L. R.
    Pamanji, R.
    Rao, J. Venkateswara
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (08) : 3462 - 3468
  • [43] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF PYROLO[2,3-D]PYRIMIDINE AND PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-B]AZEPINE DERIVATIVES
    DOZOROVA, EN
    GRIZIK, SI
    PERSIANOVA, IV
    SYUBAEV, RD
    SHVARTS, GY
    GRANIK, VG
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1985, 19 (02): : 154 - 158
  • [44] Synthesis and Antimicrobial Evaluation of Some Novel Pyrido[2,3-d] Pyrimidine Derivatives and Their Ribofuranosides
    Bhargava, Sangeeta
    Rajwanshi, Lokesh Kumar
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (08) : 1874 - 1879
  • [45] Design, synthesis, and evaluation of the anticonvulsant and antidepressant activities of pyrido[2,3-d]pyrimidine derivatives
    Hong-Jian Zhang
    Shi-Ben Wang
    Xiang Wen
    Jin-Zi Li
    Zhe-Shan Quan
    Medicinal Chemistry Research, 2016, 25 : 1287 - 1298
  • [46] Novel quinazoline and pyrido[2,3-d]pyrimidine derivatives and their hydroselenite salts as antitumoral agents
    Antonio Palop, Juan
    Plano, Daniel
    Moreno, Esther
    Sanmartin, Carmen
    ARKIVOC, 2014, : 187 - 206
  • [47] Efficient one-pot preparation of novel fused chromeno[2,3-d]pyrimidine and pyrano[2,3-d]pyrimidine derivatives
    Aly, Hala M.
    Kamal, Mona M.
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 47 : 18 - 23
  • [48] Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates
    N. M. Khalifa
    E. S. Nossier
    A. E. Amr
    Russian Journal of General Chemistry, 2018, 88 : 1228 - 1231
  • [49] Efficient Synthesis and Reactions of New Functionally Substituted Pyrido[2,3-d]pyrimidine Candidates
    Khalifa, N. M.
    Nossier, E. S.
    Amr, A. E.
    RUSSIAN JOURNAL OF GENERAL CHEMISTRY, 2018, 88 (06) : 1228 - 1231
  • [50] Microwave-assisted multicomponent reaction: An efficient synthesis of indolyl substituted and spiroxindole pyrido[2,3-d]pyrimidine derivatives
    Wang, Jing
    Zhu, Shuang
    Liu, Yanni
    Zhu, Xiaotong
    Shi, Kexin
    Li, Xiang
    Zhu, Songlei
    SYNTHETIC COMMUNICATIONS, 2022, 52 (01) : 85 - 95
12345