Enantioselective addition of diethylzinc to aryl aldehydes catalyzed by 1,2,3,4-tetrahydroisoquinoline β-amino alcohol

被引:0
|
作者
Geng Xu
机构
关键词
β-Amino alcohol; Tetrahydroisoquinoline; Diethylzinc; Asymmetric addition;
D O I
暂无
中图分类号
O643.32 [催化反应];
学科分类号
081705 ;
摘要
A highly effective,new chiral 1,2,3,4-tetrahydroisoquinoline catalyst 1 for the diethylzinc addition to aryl aldehydes has been investigated.Using 10 mol%of this chiral catalyst,secondary alcohols can be obtained in up to 87%yield and 99.5%ee under mild conditions.
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页码:309 / 311
页数:3
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