Astaxanthin attenuates contrast-induced acute kidney injury in rats by inhibiting dynaminrelated protein 1-mediated mitochondrial fission through activating SIRT1 pathway

被引：0
|
作者：
张成 [1 ]
机构：
[1] Dept Cardiol,Affil Hosp,Xuzhou Med Univ
来源：
China Medical Abstracts (Internal Medicine) | 2022年 / 39卷 / 04期
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D O I：
暂无
中图分类号：
R692 [肾疾病];
学科分类号：
1002 ; 100210 ;
摘要：
Objective To investigate whether astaxanthin(AST) down-regulates dynamin-related protein 1(Drpl) through activating the silent mating type information regulation 2 homolog-1(SIRT1) signaling pathway,thereby attenuating contrast-induced acute kidney injury.Methods Forty adult male SpragueDawley rats weighing 160-180 g were randomly divided into five groups:sham surgery group(Sham group),
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页码：227 / 228
页数：2
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