Astaxanthin attenuates contrast-induced acute kidney injury in rats by inhibiting dynaminrelated protein 1-mediated mitochondrial fission through activating SIRT1 pathway

被引：0
|
作者：
张成 [1 ]
机构：
[1] Dept Cardiol,Affil Hosp,Xuzhou Med Univ
来源：
China Medical Abstracts (Internal Medicine) | 2022年 / 39卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R692 [肾疾病];
学科分类号：
1002 ; 100210 ;
摘要：
Objective To investigate whether astaxanthin(AST) down-regulates dynamin-related protein 1(Drpl) through activating the silent mating type information regulation 2 homolog-1(SIRT1) signaling pathway,thereby attenuating contrast-induced acute kidney injury.Methods Forty adult male SpragueDawley rats weighing 160-180 g were randomly divided into five groups:sham surgery group(Sham group),
引用
下载
收藏
页码：227 / 228
页数：2
相关论文
共 50 条
  • [21] RESVERATROL PROTECTS AGAINST SPINAL CORD INJURY BY ACTIVATING AUTOPHAGY AND INHIBITING APOPTOSIS MEDIATED BY THE SIRT1/AMPK SIGNALING PATHWAY
    Zhao, Haosen
    Chen, Shurui
    Gao, Kai
    Zhou, Zipeng
    Wang, Chen
    Shen, Zhaoliang
    Guo, Yue
    Li, Zhuo
    Wan, Zhanghui
    Liu, Chang
    Mei, Xifan
    NEUROSCIENCE, 2017, 348 : 241 - 251
  • [22] Tetrahydrocurcumin protects against sepsis-induced acute kidney injury via the SIRT1 pathway
    Li, Lu
    Liu, Xiaoxi
    Li, Shasha
    Wang, Qingyan
    Wang, Hongru
    Xu, Menglu
    An, Yanxin
    RENAL FAILURE, 2021, 43 (01) : 1028 - 1040
  • [23] Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway
    Shi, Si
    Lei, Shaoqing
    Tang, Chaoliang
    Wang, Kai
    Xia, Zhongyuan
    BIOSCIENCE REPORTS, 2019, 39
  • [24] Editorial Expression of Concern: Ginkgetin aglycone ameliorates LPS-induced acute kidney injury by activating SIRT1 via inhibiting the NF-κB signaling pathway
    Junwei Zhang
    Suxia Yang
    Fang Chen
    Huicong Li
    Baoping Chen
    Cell & Bioscience, 12
  • [25] Inhibition of Drp1-mediated mitochondrial fission improves contrast-induced acute kidney injury by targeting the mROS-TXNIP-NLRP3 inflammasome axis
    Zhang, Jiong
    Wei, Qian
    Wu, Shu-kun
    Wang, Fang
    Yuan, Tong-Ling
    Wang, Jia
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 133
  • [26] Quercetin improves contrast-induced acute kidney injury through the HIF-1α/lncRNA NEAT1/HMGB1 pathway
    Luo, Min
    Liu, Ziyu
    Hu, Zongren
    He, Qinghu
    PHARMACEUTICAL BIOLOGY, 2022, 60 (01) : 889 - 898
  • [27] Agrimol B alleviates cisplatin-induced acute kidney injury by activating the Sirt1/Nrf2 signaling pathway in mice
    Tang, Jiarui
    Li, Longhui
    Chen, Zhijian
    Liao, Cuiting
    Hu, Kai
    Yang, Yongqiang
    Huang, Jiayi
    Tang, Li
    Zhang, Li
    Li, Longjiang
    ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2024, 56 (04): : 551 - 563
  • [28] Dexmedetomidine ameliorates acute kidney injury by regulating mitochondrial dynamics via the α2-AR/SIRT1/PGC-1α pathway activation in rats
    Shuai Zhang
    Xiujing Feng
    Guiyan Yang
    Haoyang Tan
    Xin Cheng
    Qichao Tang
    Haotian Yang
    Yuan Zhao
    Xuanpan Ding
    Siyao Li
    Xinyi Dou
    Junfeng Li
    Huijie Kang
    Xingxing Li
    Yaxin Ji
    Qingdian Hou
    Qiuyue An
    Hao Fang
    Honggang Fan
    Molecular Medicine, 30 (1)
  • [29] Salidroside ameliorates acetaminophen-induced acute liver injury through the inhibition of endoplasmic reticulum stress-mediated ferroptosis by activating the AMPK/SIRT1 pathway
    Xu, Jun
    Zhao, Luying
    Zhang, Xiangting
    Ying, Kanglei
    Zhou, Ruoru
    Cai, Weimin
    Wu, Xiao
    Jiang, Haoran
    Xu, Qian
    Miao, Dan
    Zeng, Yuan
    Yu, Fujun
    ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 262
  • [30] Dapagliflozin Attenuates Contrast-induced Acute Kidney Injury by Regulating the HIF-1α/HE4/NF-κB Pathway
    Huang, Xu
    Guo, Xiaoxu
    Yan, Gaoliang
    Zhang, Yang
    Yao, Yuyu
    Qiao, Yong
    Wang, Dong
    Chen, Gecai
    Zhang, Weiwei
    Tang, Chengchun
    Cao, Feng
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 2022, 79 (06) : 904 - 913
12345